Application of image-recognition techniques to automated micronucleus detection in the in vitro micronucleus assay
Hiromi Yoda,
Kazuya Abe,
Hideya Takeo
et al.
Abstract:Background
An in vitro micronucleus assay is a standard genotoxicity test. Although the technique and interpretation of the results are simple, manual counting of the total and micronucleus-containing cells in a microscopic field is tedious. To address this issue, several systems have been developed for quick and efficient micronucleus counting, including flow cytometry and automated detection based on specialized software and detection systems that analyze images.
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