Ever‐increasing demand for a healthy and sustainable life has been a traditional motivation behind state‐of‐the‐art medicines and precision diagnosis tools. Nowadays, the ultra‐connectivity and data‐centric initiatives that underpin the future Internet of Things is seen as another major driver of electronically enriched, highly customizable healthcare platforms. Especially, the information display technology, which already enjoys its position as an all‐round player in consumer electronics is poised to broaden its territory by envisioning a range of bio‐related features. In this review, the rising opportunities for next‐generation display‐based biotechnology and healthcare systems are critically assessed in light of recent literature. Clearly, smart combination of new materials, devices, and integration strategies has given rise to highly promising prototypes, and this article aims at highlighting some of these examples. Despite such progress, it is still unclear whether the resultant technologies will make a measurable impact in the near future, given both their own scientific limits and the lack of proper business model. In this regard, the final part of this contribution is dedicated to emergent challenges as well as development solutions that this potentially disruptive innovation may need to consider.