Application of fibrin sealant in patients operated on for differentiated thyroid cancer. What do we improve?

Vidal-Pérez, Óscar; Flores-Siguenza, Luis; Valentini, Mauro; Astudillo-Pombo, Emiliano; Fernández‐Cruz, Laureano; García‐Valdecasas, Juan Carlos

doi:10.1016/j.circen.2016.06.003

Cited by 6 publications

(15 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…<20 mL/24 h. The overall analysis shows a tendency for FS to reduce the mean retention time of drains by 1.24 days ( I 2 =99%, 95% CI −3.32 to 0.85, P =.25); however, there is substantial statistical heterogeneity and the difference is not statistically significant. This heterogeneity is primarily because the study by Vidal‐Perez et al . very strongly favours the use of FS compared with the other studies.…”

Section: Resultsmentioning

confidence: 99%

“…Two trials looked at the use of FS in thyroidectomy (hemi‐ and total), two at total thyroidectomy with some form of neck dissection (Kim et al . included patients having central neck dissection, whereas Vidal‐Perez et al . included patients having central and lateral neck dissections), one at lateral neck dissection, one at parotidectomy and five at rhytidectomy .…”

Section: Resultsmentioning

confidence: 99%

“…Postoperative pain was reported in three studies that found no significant difference between FS and control . All studies reported pain using visual analogue scales (VAS); only Vidal‐Perez et al.…”

Section: Resultsmentioning

confidence: 99%

“…This heterogeneity can be explained by the fact that the three studies included in this analysis incorporated different surgical procedures. Huang et al just looked at lateral neck dissection, Kim et al just looked at total thyroidectomy with central neck dissection and Vidal‐Perez et al looked at total thyroidectomy with central and lateral neck dissection. The degree of heterogeneity is compounded by the fact that Vidal‐Perez et al showed a significantly greater benefit of using FS compared to the other studies.…”

Section: Discussionmentioning

confidence: 99%

“…Huang et al just looked at lateral neck dissection, Kim et al just looked at total thyroidectomy with central neck dissection and Vidal‐Perez et al looked at total thyroidectomy with central and lateral neck dissection. The degree of heterogeneity is compounded by the fact that Vidal‐Perez et al showed a significantly greater benefit of using FS compared to the other studies. Similar effects of this study on the heterogeneity of meta‐analysis can be seen in “retention time of drains” and “hospital length of stay” (Figure ).…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Fibrin sealants in soft tissue surgery of the head and neck: A systematic review and meta‐analysis of randomised controlled trials

Bajwa

Tudur-Smith

Shaw

et al. 2017

Clinical Otolaryngology

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Fibrin sealants in soft tissue surgery of the head and neck: A systematic review and meta‐analysis of randomised controlled trials

Bajwa

Tudur-Smith

Shaw

et al. 2017

Clinical Otolaryngology

View full text Add to dashboard Cite

show abstract

Determining the effectiveness of Fibrin Sealants in reducing complications in patients undergoing lateral neck dissection

Schache¹

2018

http://isrctn.com/

View full text Add to dashboard Cite

Efficacy of four different hemostatic agents in thyroid surgery in reducing the amount of post-operative fluid collection

von Ahnen,

Militz-Müller

et al. 2023

BMC Surg

View full text Add to dashboard Cite

Purposes Postoperative bleeding remains a life-threatening complication in thyroid surgery. The aim was to assess the efficacy of four different hemostatic agents, Collagen-Fibrinogen-Thrombin Patch (CFTP) in two sizes (3 × 2.5 cm and 9.5 × 4.8 cm), polysaccharide particles (1 g) and Cellulose Gauze (2.5 × 5 cm) on postoperative drainage volume (DV) compared to a control group. Methods We included from October 2007 until Mai 2011, 150 patients (30 per group) for this monocentric, retrospective case-controlled study. Patients were scheduled for a hemithyroidectomy or thyroidectomy. The primary endpoint was the postoperative DV within the first 24 h, secondary the incidence of adverse events. Results There were no difference in demographic parameters. The mean DV (± SD) was 51.15 (± 36.86) ml in the control, 50.65 (± 42.79) ml in small (3 × 2.5 cm), 25.38 (± 23.99) ml in large CFTP (9.5 × 4.8 cm), 53.11 (± 39.48) ml in the polysaccharide particles and 48.94 (± 30.59) ml in the cellulose gauze group. DV was significantly reduced with the large CFTP (p < 0.05) compared to all other groups. There were no adverse events. Conclusions We were able to demonstrate a significant reduction in the DV for the large CFTP group compared to the other collectives. Although this as being associated with not inconsiderable costs and we would only recommend its use for high-risk patients only.

show abstract

Application of fibrin sealant in patients operated on for differentiated thyroid cancer. What do we improve?

Cited by 6 publications

References 25 publications

Fibrin sealants in soft tissue surgery of the head and neck: A systematic review and meta‐analysis of randomised controlled trials

Fibrin sealants in soft tissue surgery of the head and neck: A systematic review and meta‐analysis of randomised controlled trials

Determining the effectiveness of Fibrin Sealants in reducing complications in patients undergoing lateral neck dissection

Efficacy of four different hemostatic agents in thyroid surgery in reducing the amount of post-operative fluid collection

Contact Info

Product

Resources

About