Application of factorial experimental design on the optical absorption from glucose–insulin samples in mid-infrared spectroscopy

Romo-Cárdenas, Gerardo Salvador; Sanchez-Lopez, Juan de Dios; Luque, P.A.; Gómez-Gutiérrez, C.M.; Hipólito, Juan Iván Nieto; Camacho‐López, Santiago; Jiménez-Cruz, Arturo; Gastelum-Acosta, Carlos; Vazquez-Briseno, Mabel; Navarro-Cota, C.

doi:10.1016/j.rinp.2019.102170

Cited by 1 publication

(1 citation statement)

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“…The wavelength range of MIR covers the basic vibration and rotational absorption band of organic and inorganic molecules, which can produce strong absorption band and have unique recognizable characteristics. 62 A statistical technique for effectively assessing and comparing design structures and component effects, the factorial experiment design, proposed by Cárdenas et al 63 This technique enables the analysis of optical overlap in mixed samples containing glucose and insulin. The results showed that glucose contributed more to the absorption spectrum than insulin in the range of 1100-950 cm −1 , and the interaction between the two had no significant effect.…”

Section: Glucose Monitoring Sensormentioning

confidence: 99%

Review—Glucose Monitoring Sensors: History, Principle, and Challenges

Jing

Chang

Liu

2022

J. Electrochem. Soc.

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Blood glucose monitoring is a valuable tool for managing diabetes. In recent years, with the increase of diabetics in the world, continuous glucose monitoring (CGM) of blood sugar changes has attracted more and more researchers' attention. Among the current technologies for measuring glucose, optical and electrochemical glucose sensors are the mainstream. Here, we introduce the history of optical, electrochemical, and other sensors such as field effect transistor sensors and their advantages and disadvantages, respectively. This review summarizes the research progress and main challenges of continuous glucose monitoring technology. We found that different optical techniques have different limitations which restricts the development of optical CGM. In contrast, electrochemical glucose sensors are more feasible and reliable in implementing CGM. Therefore, this review focuses on the development and shortcomings of electrochemical sensors, especially the promising direct electron transfer and the current commercial CGM. Hopefully, it will help readers sort out the future of CGM's development.

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Section: Glucose Monitoring Sensormentioning

confidence: 99%