Abstract:Experimental design is an important chemometric tool for systemic optimization, allowing the study of a number of variables concomitantly, thus reducing the number of tests, time and reagents that are used in addition to reduce the amount of generated residues. In the present work the main objective was to use a factorial design 2 2 with central and axial points for optimization of cloud point extraction in order to determine cadmium, nickel, lead and cobalt by flame atomic absorption spectrometry. Variables t… Show more
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