For Magnitude 7.4 large-scale earthquake that occurred in Maduo County, Guoluo Prefecture, Qinghai Province in 2021, two Sentinel-1a images were used for orbit descent, one Sentinel-1a image and one Sentinel-1b image were spliced and cut, and D-InSAR technology was used for analysis. Despite extensive research into this earthquake, understanding its causes was biased due to its low coherence characteristics. In this study, we derived seismic LOS direction interferograms and coherence maps from Sentinel-1A/B data. The interferogram shows that the fault has multiple asperities and the deformation is larger as it is closer to the epicenter. According to the distribution map of the fault zone, it is concluded that the seismogenic fault is the fault zone of the southern margin of Gande. The stress analysis of the plate where the earthquake is located shows that the probability of earthquakes in the south of the Bayan Har block where the earthquake is located will increase in the future.