Application of Diamagnetic Levitation Technology in Biological Sciences Research

Qian, Airong; Yin, Da‐Chuan; Yang, Pengfei; Lv, Yiliang; Tian, Zongcheng; Shang, Peng

doi:10.1109/tasc.2012.2232919

Cited by 25 publications

(17 citation statements)

References 42 publications

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“…Diamagnetic levitation is a technique to stimulate groundbased low gravity (reviewed in Qian et al 2013). A superconducting solenoid magnet (MF in the geometric center of the solenoid was 16.5 T) was used for diamagnetic levitation of transgenic Arabidopsis thaliana ecotype Columbia seedlings containing the CycB1-GUS proliferation marker and the DR5-GUS auxin-mediated growth marker, respectively (Manzano et al 2013).…”

Section: Explanation Based On Oriented Movements Of Substancesmentioning

confidence: 99%

Magnetic fields: how is plant growth and development impacted?

2015

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This review provides detailed insight on the effects of magnetic fields on germination, growth, development, and yield of plants focusing on ex vitro growth and development and discussing the possible physiological and biochemical responses. The MFs considered in this review range from the nanoTesla (nT) to geomagnetic levels, up to very strong MFs greater than 15 Tesla (T) and also super-weak MFs (near 0 T). The theoretical bases of the action of MFs on plant growth, which are complex, are not discussed here and thus far, there is limited mathematical background about the action of MFs on plant growth. MFs can positively influence the morphogenesis of several plants which allows them to be used in practical situations. MFs have thus far been shown to modify seed germination and affect seedling growth and development in a wide range of plants, including field, fodder, and industrial crops; cereals and pseudo-cereals; grasses; herbs and medicinal plants; horticultural crops (vegetables, fruits, ornamentals); trees; and model crops. This is important since MFs may constitute a non-residual and non-toxic stimulus. In addition to presenting and summarizing the effects of MFs on plant growth and development, we also provide possible physiological and biochemical explanations for these responses including stress-related responses of plants, explanations based on dia-, para-, and ferromagnetism, oriented movements of substances, and cellular and molecular changes.

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Section: Explanation Based On Oriented Movements Of Substancesmentioning

confidence: 99%

Magnetic fields: how is plant growth and development impacted?

2015

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“…We raise a hypothesis that 16 T SMF had inhibited effects on osteoclast activity, while its formation and differentiation could be enhanced by intensities of 500 nT and 0.2 T. In order to test our hypothesis, we investigated the regulatory role of SMFs on osteoclastogenesis and the ability of the bone resorption of osteoclast precursor RAW264.7 cells under such SMFs as HyMF, GMF, MMF to HiMF. The present study utilized HyMF of about 500 nT (created by a magnetic shielding room), MMF of 0.2-0.4 T (surrounding a superconducting magnet) and HiMF of 16 T (generated by a superconducting magnet) based on our previous studies (Jia et al, 2014;Wang et al, 2009;Qian et al, 2009Qian et al, , 2013.…”

Section: Introductionmentioning

confidence: 99%

Regulation of osteoclast differentiation by static magnetic fields

Zhang

Meng

Ding

et al. 2016

Electromagnetic Biology and Medicine

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Static magnetic field (SMF) modulates bone metabolism, but little research is concerned with the effects of SMF on osteoclast. Our previous studies show that osteogenic differentiation is strongly correlated with magnetic strength from hypo (500 nT), weak (geomagnetic field, GMF), moderate (0.2 T) to high (16 T) SMFs. We speculated that the intensity that had positive (16 T) or negative (500 nT and 0.2 T) effects on osteoblast differentiation would inversely influence osteoclast differentiation. To answer this question, we examined the profound effects of SMFs on osteoclast differentiation from pre-osteoclast Raw264.7 cells. Here, we demonstrated that 500 nT and 0.2 T SMFs promoted osteoclast differentiation, formation and resorption, while 16 T had an inhibitory effect. Almost all the osteoclastogenic genes were highly expressed under 500 nT and 0.2 T, including RANK, matrix metalloproteinase 9 (MMP9), V-ATPase, carbonic anhydrase II (Car2) and cathepsin K (CTSK), whereas they were decreased under 16 T. In addition, 16 T disrupted actin formation with remarkably decreased integrin β3 expression. Collectively, these results indicate that osteoclast differentiation could be regulated by altering the intensity of SMF, which is just contrary to that on osteoblast differentiation. Therefore, studies of SMF effects could reveal some parameters that could be used as a physical therapy for various bone disorders.

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“…For more detailed information and specific parameters about the platform, please refer to papers by Qian et al (2009Qian et al ( , 2013.…”

Section: Illumination Device For Diamagnetic Levitation In a Super Comentioning

confidence: 99%

“…In diamagnetic levitation the same magnetic force is applied to each part of the diamagnetic materials and thus it is a stable system and a valuable and suitable simulation technology for long biological experiments. Diamagnetic levitation is a new and potentially transformative method to explore how gravity affects living organisms and many researchers have begun to use it in their studies (Valles et al, 1997;Liu et al, 2010Liu et al, , 2011Herranz et al, 2012;Tian et al, 2010;Qian et al, 2009Qian et al, , 2013Gao et al, 2010;Dijkstra et al, 2011;Yan et al, 2012).…”

Section: Introductionmentioning

confidence: 99%