2022
DOI: 10.3390/antibiotics11111593
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Application of Decision-Tree-Based Machine Learning Algorithms for Prediction of Antimicrobial Resistance

Abstract: Timely and efficacious antibiotic treatment depends on precise and quick in silico antimicrobial-resistance predictions. Limited treatment choices due to antimicrobial resistance (AMR) highlight the necessity to optimize the available diagnostics. AMR can be explicitly anticipated on the basis of genome sequence. In this study, we used transcriptomes of 410 multidrug-resistant isolates of Pseudomonas aeruginosa. We trained 10 machine learning (ML) classifiers on the basis of data on gene expression (GEXP) info… Show more

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Cited by 17 publications
(20 citation statements)
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“…The application of a metaclassifier proved to be the most effective model for identifying blackcurrant powders. The ensembles of classifiers extracting single classifiers, i.e., random forest, decision tree, or bagging have become a better solution than the existing neural modeling tools [ 47 , 55 , 58 , 63 , 72 ]. But the important thing is that the choice of method depends on the specific task at hand and the number of cases in the learning set.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…The application of a metaclassifier proved to be the most effective model for identifying blackcurrant powders. The ensembles of classifiers extracting single classifiers, i.e., random forest, decision tree, or bagging have become a better solution than the existing neural modeling tools [ 47 , 55 , 58 , 63 , 72 ]. But the important thing is that the choice of method depends on the specific task at hand and the number of cases in the learning set.…”
Section: Resultsmentioning
confidence: 99%
“…It can be a very flexible yet effective model, especially in the classification aspect. Another algorithm is RidgeClassifier based on ridge regression [ 58 ]. This model was characterized by a high need for data control in optimizing the results, among other things.…”
Section: Methodsmentioning
confidence: 99%
“…Therefore, it is possible to understand the features or interaction of features responsible for a particular decision. Gradient-boosting models—ensemble methods from decision tree—have been successfully used in AMR prediction [ 28 , 72 , 73 ]. Table 1 shows different DL/ML models used in AMR identification and applications.…”
Section: Artificial Intelligence (Dl/ml) For Antimicrobial Resistancementioning
confidence: 99%
“…A decision tree might be used to identify asthma from a patient's wheezing, coughing, and shortness of breath (Tyagi & Singh, 2014). Based on clinical data, decision trees can be used to choose the best course of treatment for a patient (Yasir et al, 2022). The optimal course of action for a patient with heart disease, for instance, can be decided using a decision tree depending on the condition of the patient, age, blood pressure, lipid profile, and other alarming factors.…”
Section: Applications Of Deep and Machine Learning In Medical Fieldsmentioning
confidence: 99%