Application of Computer Modelling in Predicting Endocrine Disrupting Chemicals Functions

Abstract

Crystal structures of proteins are necessary in controlling the mechanism between Endocrine Disrupting Chemicals and protein receptors. However there lacks the researches protein structures delay. The strategy of computing including homology modelling and docking method can be used to fill up the gap. Up to now, homology modelling is the best way to obtain useful structures. Meanwhile docking is used in protein ligand researches. The corresponding computational tools are helpful to carry on the research on the endocrine disrupting mechanism which is triggered by receptor ligand interaction.