This publication deals with the practical challenge of describing the impurity influence on the fixed-point temperature of zinc. For this, the sum of individual estimate (SIE) approach is applied to miniaturized fixed-point cells (MFPC) filled with high-purity zinc that can be used in industrial applications. This includes comparative analyses by glow discharge mass spectroscopy as well as mass spectroscopy with inductive coupled plasma to quantify the impurity concentrations in zinc. Furthermore, the element-specific and concentration-dependent temperature deviations are presented for the fixed-point material zinc. For this, binary phase diagrams as well as thermal calculations and experimental data were analysed to extract the relevant sensitivity coefficients. Besides, results from SIE analyses of MFPCs are presented and their uncertainties are compared. On this basis, practical limits of the SIE method are identified and discussed.