Application of Bicuculline to the Gerbil Somatosensory Cortex Induces Repetitive Ear Movements Accompanied by Induction of c-Fos Immunoreactivity in the Thalamus.
Abstract:We previously established a seizuresensitive strain of Mongolian gerbil, MGS/ Idr, in which seizure-inducing stimuli often elicit repetitive backward jerks of the ears at the beginning of seizures, and found that unilateral application of (-)-bicuculline methiodide (BMI) to an area of the somatosensory cortex in this strain induced similar, but long-lasting, repetitive movements of the contralateral ear. In the present study, we have extended this observation by using immunohistochemistry to look for areas of … Show more
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