The method of bi-dimensional empirical mode decomposition (BEMD) and the combined methods of entropy weight-Technique for Order of Preference by Similarity to an Ideal Solution (TOPSIS) were used to decompose gravity-magnetic data and evaluate targets in the Luziyuan Pb-Zn-Fe polymetallic ore field and surrounding areas. Three meaningful bidimensional intrinsic mode function (BIMF) images were obtained by BEMD at different wavelengths, depicting different layers of geological architectures in the study area. The results are as follows. (1) The BIMF2 images depict the shallow local geological architecture and show positive gravity-magnetic anomalies of the skarn alteration and Pb-Zn-Fe mineralization distributed around concealed granites. (2) The BIMF3 images depict the medium-depth geological architecture, indicating that concealed granitic stocks, which are shallow extensions of a deeply concealed pluton, intruded along the NE-trending fault. (3) The BIMF4 images depict gravity-magnetic anomalies at greater depth, which likely reflect regional geological architectures, indicating the potential presence of a large, concealed intermediate-acid pluton in the negative anomaly zone. Three potential targets (A, B, and C) were delineated based on BEMD results of the original gravity-magnetic data. The entropy weight-TOPSIS evaluation results show that the ranking of the metallogenic potential of the delineated targets in the study area is B, A, and C, with relative proximity values of 0.4576, 0.3925, and 0.1499, respectively. The results of this study can be used to guide future exploration.