Application of backward diffuse reflection spectroscopy for monitoring the state of tissues in photodynamic therapy

Stratonnikov, Alexander A.; Меерович, Г. А.; Ryabova, Anastasia V.; Савельева, Т. А.; Loschenov, Viktor

doi:10.1070/qe2006v036n12abeh013331

Cited by 17 publications

(10 citation statements)

References 6 publications

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“…This technique is only applicable in a medium where absorption and scattering are relatively homogeneous. 35 In skin, where areas of high scattering (e.g., deep epidermis) and high absorption (such as those found in PWS skin) exist, the Beer-Lambert Law is not appropriate. Furthermore, it is not possible to account for the effects of vascular architecture in PWS skin using this method alone.…”

Section: Beer-lambert Lawmentioning

confidence: 99%

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Simulating light transport through skin for color prediction of port wine stain lesions: a review

2012

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Abstract. A survey of the literature is presented regarding the simulation of port wine stain (PWS) skin color. Knowledge of PWS features, such as the depths and diameters of affected vessels, is essential for informing laser treatment. These may be determined through the inverse application of a skin model. The techniques which have been applied to achieve this are analyzed in detail. Radiative transfer (RT) is found to be the preferred method of simulation. By far the most common approximations to RT are the diffusion approximations, which have been applied successfully in the past and Monte Carlo techniques, which are now the methods of choice. As the requirements for improvement of laser treatment on an individual basis continues, the needs for further work towards accurate estimations of individual optical coefficients and robust, flexible simulation techniques are identified.

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Section: Beer-lambert Lawmentioning

confidence: 99%

“…[33][34][35] These generally involve an additional exponential term to describe loss due to scattering and use an approximation of the mean optical path length hli, for example:…”

Section: Beer-lambert Lawmentioning

confidence: 99%

Simulating light transport through skin for color prediction of port wine stain lesions: a review

2012

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“…More recently, the introduction of skin color measurements has extended this to include the potential for objective determination of skin features, 1 including melanin and hemoglobin concentrations, 2-6 the depth and diameter of blood vessels, 7-9 the depth of pigmented skin lesions, 10,11 the maturity and depth of bruises, 12,13 and keratin fiber arrangements. 14 Such advances have proved invaluable for the advancement of skin laser treatments 15 and photodynamic therapy, [16][17][18] and have contributed to further advances in the diagnosis of cancerous and noncancerous skin lesions. 10,[19][20][21] However, the success of these methods depends entirely upon adequate knowledge of the behavior of light as it impinges upon, and travels through, the skin.…”

Section: Introductionmentioning

confidence: 99%

Optical properties of human skin

2012

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Abstract. A survey of the literature is presented that provides an analysis of the optical properties of human skin, with particular regard to their applications in medicine. Included is a description of the primary interactions of light with skin and how these are commonly estimated using radiative transfer theory (RTT). This is followed by analysis of measured RTT coefficients available in the literature. Orders of magnitude differences are found within published absorption and reduced-scattering coefficients. Causes for these discrepancies are discussed in detail, including contrasts between data acquired in vitro and in vivo. An analysis of the phase functions applied in skin optics, along with the remaining optical coefficients (anisotropy factors and refractive indices) is also included. The survey concludes that further work in the field is necessary to establish a definitive range of realistic coefficients for clinically normal skin.

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“…We know that the diffuse reflection coefficient R depends first of all on the absorption coefficient a and the reduced scattering coefficient μ s ′ , and also on the spatial distribution of these coefficients in biological tissue [4].…”

Section: Development Of the Technique And Selection Of The Model Paramentioning

confidence: 99%

Analysis of the biochemical composition of biological tissue in vivo by the diffuse light scattering method

Saetchnikov

Tcherniavskaia

2011

J Appl Spectrosc

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Application of backward diffuse reflection spectroscopy for monitoring the state of tissues in photodynamic therapy

Cited by 17 publications

References 6 publications

Simulating light transport through skin for color prediction of port wine stain lesions: a review

Simulating light transport through skin for color prediction of port wine stain lesions: a review

Optical properties of human skin

Analysis of the biochemical composition of biological tissue in vivo by the diffuse light scattering method

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