Application of Anterior Segment Optical Coherence Tomography in Pediatric Ophthalmology

Abstract

Purpose. Application of anterior segment optical coherence (AS-OCT) in pediatric ophthalmology. Methods. Retrospective clinical study case series of 26 eyes of 19 pediatric patients throughout a 21-month period, presenting anterior segment pathologies, were submitted to AS-OCT examination (OCT Visante, 1310 nm, Zeiss), noncontact technique, no sedation requirement. Results. AS-OCT images were obtained from 19 patients (range: 2 months to 12 years). Clinical diagnosis of anterior segment abnormalities included cornea disease (n = 7), congenital anterior segment conditions (n = 10), ocular trauma (n = 1), anterior segment surgeries (n = 2), iridocorneal angle abnormalities (n = 4), intermediate uveitis (n = 2). The most common OCT findings were corneal hyperreflectivity and thickening (n = 15), shallow anterior chamber with iris-lens diaphragm anterior displacement (n = 4), atypical corneal curvature (n = 4), corneal thinning (n = 4), peripheral synechiae with angle closure (n = 3), increased anterior chamber depth (n = 2), and proximal portion of glaucoma drainage tube (n = 2). Conclusion. In the present study, noncontact AS-OCT demonstrated to be a feasible technique to evaluate the anterior segment providing anatomic details and useful to clarify diagnosis in the pediatric population.

A rare case of type 1 unilateral 'peripheral' Peters' anomaly

“…In their study, mesodermal dysgenesis (Peters’ anomaly in two eyes) was demonstrated as increased reflectivity of the central cornea (leukoma) associated with local indentation (malformation) of the posterior surface (Descemet's membrane defect), with overall increased stromal reflectivity and thickness. [5] We confirmed the diagnosis of our case based on similar findings in OCT.…”

Anterior Segment Optical Coherence Tomography in Pediatric Ocular Pathology: Imaging Study of 115 eyes

“…Cauduro et al 9 have beautifully described the usage of AS-OCT in pediatric ophthalmology in 26 eyes of 19 children with various anterior segment diseases in their article, and have labelled it feasible in clarifying diagnosis, and surgical planning and follow up. Majander 10 et al have utilized this technique with extensive benefit in pediatric eyes of 7 patients with varying causes of congenital corneal opacities.…”

OCT on Anterior Segment Anomalies of the Eye in a Polish Paediatric Cohort: Diagnostic and Therapeutic Challenges

“…Cauduro et al point out that in the case of paediatric diagnostics of acquired and congenital defects in the anterior segment, OCT provides invaluable services [ 6 ]. Optical tomography supports a topographic diagnosis of the anatomy of the anterior chamber that accounts for the position of the iris-lens diaphragm.…”