Application of acoustic radiation force in ophthalmic ultrasound

Walker, William F.; Davidsen, R.E.; Toth, Cynthia A.

doi:10.1109/ultsym.1997.661814

Cited by 5 publications

(3 citation statements)

References 6 publications

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“…Alternatively, the shear modulus can be estimated directly within the ROE [7], [11], [14], [23], [24] based on the displacement measured within ROE. However, a common problem in such acoustic radiation force-based imaging techniques is that the magnitude of the force applied to any targets depends on acoustic properties of the medium because ultrasound waves attenuate unpredictably as they propagate deeper into tissue.…”

Section: Introductionmentioning

confidence: 99%

Assessment of shear modulus of tissue using ultrasound radiation force acting on a spherical acoustic inhomogeneity

Karpiouk

Aglyamov

Ilinskii

et al. 2009

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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An ultrasound-based method to locally assess the shear modulus of a medium is reported. The proposed approach is based on the application of an impulse acoustic radiation force to an inhomogeneity in the medium and subsequent monitoring of the spatio-temporal response. In our experimental studies, a short pulse produced by a 1.5-MHz highly focused ultrasound transducer was used to initiate the motion of a rigid sphere embedded into an elastic medium. Another 25 MHz focused ultrasound transducer operating in pulse-echo mode was used to track the displacement of the sphere. The experiments were performed in gel phantoms with varying shear modulus to demonstrate the relationship between the displacement of the sphere and shear modulus of the surrounding medium. Because the magnitude of acoustic force applied to sphere depends on the acoustic material properties and, therefore, cannot be used to assess the absolute value of shear modulus, the temporal behavior of the displacement of the sphere was analyzed. The results of this study indicate that there is a strong correlation between the shear modulus of a medium and spatio-temporal characteristics of the motion of the rigid sphere embedded in this medium.

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Section: Introductionmentioning

confidence: 99%

Assessment of shear modulus of tissue using ultrasound radiation force acting on a spherical acoustic inhomogeneity

Karpiouk

Aglyamov

Ilinskii

et al. 2009

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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“…These approaches are quite elegant, but may be unable to generate measurable strains or displacements in deep-lying tissues and soft tissue within harder shells. A number of alternative techniques may avoid this limitation by utilizing acoustic radiation force to apply forces internally, and employing either audio (Fatemi and Greenleaf 1996) or ultrasonic (Sugimoto et al 1990, Sarvazyan et al 1998, Walker et al 1997 methods to detect resulting displacements. These methods, however, are unlikely to achieve the larger forces available by direct application of force at the tissue surface (Walker 1999).…”

Section: Introductionmentioning

confidence: 99%

“…We have previously described a method for forming images of tissue stiffness using acoustic radiation force (Walker et al 1997). This approach is shown schematically in figure 1.…”

Section: Introductionmentioning

confidence: 99%

A method of imaging viscoelastic parameters with acoustic radiation force

2000

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Acoustic radiation force has been proposed as a method of interrogating the mechanical properties of tissue. One simple approach applies a series of focused ultrasonic pulses to generate an acoustic radiation force, then processes the echoes returned from these pulses to estimate the radiation-force-induced displacement as a function of time. This process can be repeated at a number of locations to acquire data for image formation. In previous work we have formed images of tissue stiffness by depicting the maximum displacement induced at each tissue location after a finite period of insonification. While these maximum displacement images are able to differentiate materials of disparate mechanical properties, they exploit only a fraction of the information available. In this paper we show that the time-displacement curves acquired from tissue mimicking phantoms exhibit a viscoelastic response which is accurately described by the Voigt model. We describe how the viscous and elastic parameters of this model may be determined from experimental data. Finally, we show phantom images that depict not only the maximum local displacement, but also the viscous and elastic model parameters. These images offer complementary information about the target.

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Diagnostic ultrasound power meter

Lim

Dove²,

Bones³

Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37

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Application of acoustic radiation force in ophthalmic ultrasound

Cited by 5 publications

References 6 publications

Assessment of shear modulus of tissue using ultrasound radiation force acting on a spherical acoustic inhomogeneity

Assessment of shear modulus of tissue using ultrasound radiation force acting on a spherical acoustic inhomogeneity

A method of imaging viscoelastic parameters with acoustic radiation force

Diagnostic ultrasound power meter

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