Application of a reversed-phase ionic liquid dispersive liquid-liquid microextraction method for the extraction and preconcentration of domoic acid from urine samples

A comparative study of ammonia solubility in imidazolium-based ionic liquids with different structural compositions

“…A mixed solvent system, incorporating various molar ratios of water and methanol,was also reported to enhance NH 3 solubility [ 5 ]. Furthermore, NH 3 solubility in aqueous solutions containing NaCl, NaNO 3 , CH 3 COONa, and NaSO 4 has been investigated within the temperature range of 313–393 K [ 6 , 7 ]. NH 3 solubility in aqueous solutions tends to decrease with increasing temperature.…”

Application of instantaneous nebulization dispersive liquid‐phase microextraction combined with HPLC for the determination of chalcone and isoflavone in traditional Chinese medicines

“…In DLPME, the extractant and dispersant are injected into the sample solution at the same time, then the extractant is dispersed into tiny droplets for extraction, and finally it sinks to the bottom or floats on the liquid surface to achieve phase separation. Due to its simple operation, rapidity, and high enrichment factor (EF), it has been widely used in the extraction and enrichment of trace compounds in various complex matrices such as TCMs, food, environmental water, plasma, urine, and other samples [19][20][21][22][23].…”

Online highly selective recognition of domoic acid by an aptamer@MOFs affinity monolithic column coupled with HPLC for shellfish safety monitoring

“…16 Though the traditional SPE and MSPE techniques are currently widely adopted and exhibit effective extraction performance, there still are problems to be resolved, such as high solvent consumption, high particle dispersity, and unsatisfactory selectivity. 6,8,17 Further, these methods are usually used in an offline manual way and hardly online coupled with LC for automatic analysis, 6,18 resulting in a number of issues, such as non-automated operation, multiple steps, analyte loss, long-time operation periods, and low efficiency. Improvements that have attached attention including attempts to automate the techniques, since SPE and MSPE processes generally require offline procedures (loading, washing, elution) and do not seem to be particularly able to cope with batch samples.…”

“…5 Due to the low content of DA in natural shellsh with complicated matrixes, it is hard to directly achieve the precise quantitation of DA by common HPLC-UV methods. 6,7 Pretreatment is necessary, and therefore, developing an efficient recognition strategy that can be online integrated with HPLC for the automatic analysis of DA with good selectivity and sensitivity would be signicant. Some common methods such as the traditional liquid-liquid extraction (LLE) 8,9 and solid-phase extraction (SPE) 10 have been reported for the DA extraction.…”