A mass transfer cavitation model for binary alkane mixtures is proposed, implemented into the in-house CFD code hydRUB and applied to a hydrofoil test case. A binary n-dodecane/n-heptane mixture at two different temperatures is considered. The saturation pressure of n-heptane and n-dodecane differs more than two orders of magnitude, so the evaporation rate of the lighter n-heptane is much higher than the one of the heavier n-dodecane. Therefore, cavitation leads to an enrichment of n-heptane in the vapor phase. This is associated with a slight densification, i.e., enrichment of n-dodecane in the liquid phase, which means that local segregation of both species occurs. With increasing temperature, the amount of n-dodecane in the vapor phase is substantially increased since the saturation pressures of both species approach. Therefore, species mass transfer deviates much less and segregation is less pronounced for the higher temperature compared to the lower one.