Application of a new multi-locus variable number tandem repeat analysis (MLVA) scheme for the seasonal investigation of Cryptosporidium parvum cases in Wales and the northwest of England, spring 2022

Risby, Harriet; Robinson, Guy; Chandra, Nastassya; King, Grace; Vivancos, Roberto; Smith, Robert; Thomas, Daniel; Fox, Andrew; McCarthy, Noel; Chalmers, Rachel M.

doi:10.1016/j.crpvbd.2023.100151

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2023

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“…Ongoing gp60 subtyping may yield large unexplained clusters warranting further investigation. Furthermore, continuation of a sentinel scheme to detect genetic clusters of C. parvum by multilocus variable number tandem repeat analysis (MLVA) [7] initiated as a pilot in Wales and the north-west of England [8] has yet to identify any notable clusters during this exceedance.…”

Section: Discussionmentioning

confidence: 99%

Preliminary investigation of a significant national Cryptosporidium exceedance in the United Kingdom, August 2023 and ongoing

Peake,

Inns,

Jarvis

et al. 2023

Eurosurveillance

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Routine laboratory surveillance has identified an unprecedented and ongoing exceedance of Cryptosporidium spp. across the United Kingdom, notably driven by C. hominis transmission, since 14 August 2023. Information from 477 reported cases in England and Wales, followed up with a standardised exposure questionnaire as of 25 September 2023, identified foreign travel in 250 (54%) of 463 respondents and swimming in 234 (66%) of 353 cases. A significant, common exposure has not yet been identified in first analyses.

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Section: Discussionmentioning

confidence: 99%