Application of a Carbon‐Paste Electrode Modified with 2,7‐Bis(ferrocenyl ethyl)fluoren‐9‐one and Carbon Nanotubes for Voltammetric Determination of Levodopa in the Presence of Uric Acid and Folic Acid

Abstract

A carbon-paste electrode modified with 2,7-bis(ferrocenyl ethyl)fluoren-9-one and carbon nanotubes was used for the sensitive voltammetric determination of levodopa (LD). The electrochemical response characteristics of the modified electrode toward LD, uric acid (UA) and folic acid (FA) were investigated. The results showed an efficient catalytic activity of the electrode for the electrooxidation of LD, which leads to lowering its overpotential by more than 320 mV. The modified electrode exhibits an efficient electron mediating behavior together with well-separated oxidation peaks for LD, UA and FA. Also, the modified electrode was used for determination of LD in some real samples.

Surfactant modified carbon nanotube paste electrode for the sensitive determination of mitoxantrone anticancer drug

“…The anodic peak potential of MTX is shifted negatively with the increase of the pH value, indicating reactions accompanied by proton transfer. The slopes of 63.6 mV/pH for MTX oxidation is nearby to the theoretical value of 59 mV/pH and pointed out toward two protons and two electrons involved in the oxidation process [28][29][30]. The detection limit (LOD) was estimated by applying the standard formula of LOD = 3sb/m [31], where m is the slope of the calibration curve and sb is the standard deviation of the peak currents of the blank solution (five replicates).…”

Electrochemical behavior of isoproterenol in the presence of uric acid and folic acid at a carbon paste electrode modified with 2,7-bis(ferrocenyl ethyl)fluoren-9-one and carbon nanotubes

“…Therefore, its determination in physiological fluids is necessary in the diagnosis and treatment of diseases such as gout, hyperuricemia, heavy hepatitis, and Lesch-Nyhan syndrome [11]. UA is also a marker for renal failure as well as toxicity.…”

Elaboration of modified poly(Ni II -DHS) films as electrodes by the electropolymerization of Ni(II)-[5,5′-dihydroxysalen] onto indium tin oxide surface and study of their electrocatalytic behavior toward aliphatic alcohols

“…Thus, some references may be mentioned: for instance, the determination of captopril, thioguanine and levodopa (Beitollahi et al, 2014(Beitollahi et al, , 2011a(Beitollahi et al, , 2011b, L-cysteine with ascorbic acid, (Raoof et al, 2007(Raoof et al, , 2006a(Raoof et al, , 2006b, hydroquinone derivatives (Taleat et al, 2008) and simultaneous determinations of carbidapa (Tajik et al, 2013).…”