2022
DOI: 10.1039/d2bm00709f
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Application and development of 3D bioprinting in cartilage tissue engineering

Abstract: Articular cartilage defects are one of the most common clinical diseases of bone articulation. Early repair of damaged joint cartilage can effectively stop the progression of arthritis and restore health...

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Cited by 23 publications
(20 citation statements)
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References 187 publications
(227 reference statements)
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“…Seed cells, scaffold materials, and growth factors were researched and improved to achieve optimization of engineered cartilage 2 . Techniques of constructing scaffolds, including 3D bioprinting (such as inkjet bioprinting, laser‐assisted bioprinting, extrusion‐based bioprinting, acoustic bioprinting, stereolithography bioprinting, and magnetic bioprinting), direct moulding methods (such as cell sheet stacking, lithography, and injection moulding), and a group of methods for constructing porous scaffolds (such as electrospinning, phase separation, freeze‐drying, and self‐assembly), are also important to elevating cartilage performance 3–6 . Nowadays, 3D bioprinting, as a form of cell‐laden bottom‐up additive manufacturing, has become one of the most promising and advanced tissue engineering methods.…”
Section: Introductionmentioning
confidence: 99%
“…Seed cells, scaffold materials, and growth factors were researched and improved to achieve optimization of engineered cartilage 2 . Techniques of constructing scaffolds, including 3D bioprinting (such as inkjet bioprinting, laser‐assisted bioprinting, extrusion‐based bioprinting, acoustic bioprinting, stereolithography bioprinting, and magnetic bioprinting), direct moulding methods (such as cell sheet stacking, lithography, and injection moulding), and a group of methods for constructing porous scaffolds (such as electrospinning, phase separation, freeze‐drying, and self‐assembly), are also important to elevating cartilage performance 3–6 . Nowadays, 3D bioprinting, as a form of cell‐laden bottom‐up additive manufacturing, has become one of the most promising and advanced tissue engineering methods.…”
Section: Introductionmentioning
confidence: 99%
“…26 Gelatin is also an attractive choice owing to its biocompatibility, biodegradability, and ability to mimic some aspects of the ECM properties, making it a suitable component for composite hydrogels in tissue engineering applications. 14…”
Section: Introductionmentioning
confidence: 99%
“…H 2 O 2 -mediated hydrogelation has been applied to create hydrogels from various polymer solutions for diverse biomedical applications. [10][11][12][13][14] Hydrogels are water-swollen networks of polymer chains that are commonly used for in vitro cell culture applications owing to their high biocompatibility, degradability, and similarity to the natural extracellular matrix (ECM). [15][16][17][18] Hydrogels can be designed with various physical, chemical, and biological properties, such as stiffness, porosity, and specific moieties that interact with cell surface receptors.…”
Section: Introductionmentioning
confidence: 99%
“…In the past decade, graphene and its derivatives were investigated for a variety of applications spanning from catalytic uses to sensing, pharmaceutical systems, and tissue engineering. [6][7][8] These nanostructured carbonaceous materials offer distinct features where the unique value of graphene in bone restoration is best shown by its mechanical qualities, such as strength, stiffness, or exibility. [9][10][11] Furthermore, graphene oxide (GO) provides reactive functional groups that encourage cell attachment and surface chemistry with other compounds.…”
Section: Introductionmentioning
confidence: 99%