“…In many studies dealing with FO operating variables on real or synthetic feeds [ 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 ], concentration, or a proxy for concentration (permeate volume, concentration factor), was used instead of osmotic pressure gradient which obfuscates the impact of variable changes with osmotic pressure changes on kinetics. In the few cases where the osmotic pressure gradient was used [ 32 , 33 , 34 ] with real feeds, few operating variables were investigated, and they tested low osmotic pressure feeds (less than 20 bar). To assess the impact of an operating variable on FO performance for any feed, it is necessary to evaluate the above operating variables under similar bulk osmotic pressure gradients, or else it is impossible to separate the effect of the variable from the driving force.…”