Appendix

Fest, Christa; Schmidt, Karl-Julius

doi:10.1007/978-3-642-68441-8_5

Cited by 2 publications

(4 citation statements)

References 447 publications

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“…The IR spectra of compounds (3)(4)(5) showed N-CH2 and the bands at 1550 cm -1 merged. It was caused by a sharp band observed at 1240-1291 cm -1 (P=O), and a band for P-C stretching appeared at 740-770 cm -1 .…”

Section: Resultsmentioning

confidence: 99%

“…All stretching frequencies are compiled in Table 2. H NMR spectra of compounds (3)(4)(5) in 1DMSO-d6 solvent were recorded. Aromatic protons of α-aminophosphonic acids appeared as a multiplet in the d-6.15-8.69 region.…”

Section: Resultsmentioning

confidence: 99%

“…Organophosphorus compounds are ubiquitous in nature and are used in agriculture, medicine, and industry [1][2][3]. Some organophosphorus compounds are important pesticides [4], bactericides [5][6][7] and antibiotics [5]. Phosphorus analogs of α-pyrones act as HIV protease inhibitors [8].…”

Section: Introductionmentioning

confidence: 99%

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Kabachnik-Fields reactions of 2,3-Trimethylene-1,2,3,4-dihydrobenzo[2,3-d]pyrimidin-4-on

Tukhsanov,

Oripov,

Haydarov

et al. 2023

E3S Web of Conf.

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In this research article, 2,3-trimethylene-3,4-dihydrobenzo[2,3-d]pyrimidin-4-one was synthesized from 2-aminobenzoic acid and pyrrolidone-2 in the presence of various substances, such as PCl5, POCl3. Its reduction reaction with NaBH4 was carried out. The resulting three-component coupling of 2,3-trimethylene-1,2,3,4-tetrahydrobenzo[2,3-d]pyrimidin-4-one-carbonyl, amine, and hydrophosphoryl leads to αaminophosphonates. Phosphate acid – formaldehyde; aldehydes in the three-component system; and the synthesis of aminomethylphosphonic acid is based on the condensation reaction. During the experiment, 2,3-trimethylene-3,4-dihydrobenzo[2,3-d]pyrimidin-4-one was obtained in the amount of 74%. The yield of the reaction product was increased in resyntheses. The structures were confirmed by IR and 1H NMR spectroscopies. Using NaBH4, the experiment was repeated and the product obtained from the synthesis of 2,3-trimethylene-1,2,3,4-tetrahydrobenzo[2,3d]pyrimidin-4-one was obtained in high yield. Additionally, 2,3-trimethylene-1,2,3,4-tetrahydrobenzo[2,3-d]pyrimidin-4-one and related aminophosphonic acids three ring molecules were synthesized in high yield.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Kabachnik-Fields reactions of 2,3-Trimethylene-1,2,3,4-dihydrobenzo[2,3-d]pyrimidin-4-on

Tukhsanov,

Oripov,

Haydarov

et al. 2023

E3S Web of Conf.

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show abstract

“…12–15 As a result, thiophosphines (R 2 P-SR 1 ), phosphinothioates (R 2 P(O)-SR), phosphonodithioates (RP(O)-(SR 1 ) 2 ), and phosphorothioates (RO) 2 P(O)-SR 1 find wide applications in diverse fields. They are important agrichemicals such as pesticides 16 and fungicides. 17 They are ubiquitous structural units in many medicines such as antibacterial agents 18–20 and used for the treatment of various ailments, including glaucoma, heart failure, and cancer.…”

Section: Introductionmentioning

confidence: 99%