Appendicular tuberculosis: a less encountered clinical entity

Ambekar, Sachin; Bhatia, Mohit

doi:10.1136/bcr-2020-237718

Cited by 5 publications

(7 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Weight loss and anorexia are less commonly documented in appendiceal tuberculosis cases. The duration of symptoms varies, ranging from 30 hours of acute symptoms to 7 months of chronic symptoms, from cases reviewed 7 9 10…”

Section: Discussionmentioning

confidence: 99%

Mycobacterium bovisinfection of the appendix: a case of appendiceal tuberculosis in rural England

Miles,

Spellar,

Williams

2024

BMJ Case Rep

View full text Add to dashboard Cite

Appendiceal tuberculosis is a rare mimic of acute appendicitis, demonstrated by several case reports of patients from tuberculosis endemic countries. On literature review, there are few cases reported of appendiceal tuberculosis in urban England, and no reports from rural England. This case describes a patient with primary appendiceal tuberculosis from a remote district hospital in England who underwent a diagnostic laparoscopy for suspected acute appendicitis. Intraoperatively, an abnormal appearance with extensive intra-abdominal adhesions was seen in addition to appendicitis, making the diagnosis dubious. Histology of the appendix was positive for acid-fast bacilli and culture of the intra-abdominal fluid revealed a diagnosis ofMycobacterium bovisinfection. The mode of infection was thought to be reactivation of latent bovine tuberculosis from drinking unpasteurised milk in adolescence. Taking a focused history, particularly in those with a farming background, and intraoperative sampling for histology and culture are vital in the diagnosis of appendiceal tuberculosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Mycobacterium bovisinfection of the appendix: a case of appendiceal tuberculosis in rural England

Miles,

Spellar,

Williams

2024

BMJ Case Rep

View full text Add to dashboard Cite

show abstract

“…Hence, granulomatous appendicitis can be linked to various diseases, including infectious conditions such as Yersinia Enterolitica and parasitic infections. Additionally, non-infectious causes, like Crohn's disease, sarcoidosis, diverticulitis, and the presence of foreign bodies, may also be associated [ 2 , 19 , 20 ].…”

Section: Discussionmentioning

confidence: 99%

“…Pulmonary TB is the most common site involved with a number of 5.3 million people worldwide in 2021 [ 1 ]. Gastrointestinal TB represents 3% of extrapulmonary TB and concerns primarily the ileocecal region [ 2 ]. Primary TB of the appendix is a rare entity with a prevalence of 0.1% to 3% in all appendicectomies performed [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

A Rare Case of Tuberculosis Revealed by Acute Appendicitis: A Case Report

Haddad,

Afifi,

El Rhaoussi

et al. 2024

Cureus

View full text Add to dashboard Cite

According to the World Health Organization (WHO), tuberculosis (TB) is the 13th cause of death worldwide and the second infectious killer after HIV. It is an endemic disease in Morocco. Isolated appendicular TB is an uncommon form of extrapulmonary TB. We report a case of a 26-year-old woman admitted for acute abdominal pain in the right iliac fossa with fever, vomiting, and diarrhea. Physical examination and abdominal ultrasound confirmed appendicitis. Surgery was performed and revealed on histopathological examination of the resected appendix the diagnosis of tubercular appendicitis. The patient was initiated on the conventional antitubercular regimen for six months and would be followed up appropriately. This case report highlights the importance of histopathological examination of appendicectomy specimens in order to diagnose rare diseases such as primary TB of the appendix.

show abstract

“…The third type presents as an incidental histopathological finding of appendicular TB with ulcerative type of appendicular appendicitis as the most common form on histopathology finding. 10,13,16,17 These non-specific symptoms eventually can delay a patient's treatment which leads to severity of the case and becomes a problem to establish the diagnosis, as stated by World Health Organization (WHO) that the diagnosis of extrapulmonary TB should be made on the basis of a culture-positive specimen or caseating granuloma on biopsy or strong clinical evidence consistent with active extrapulmonary TB. MTB in GI TB is pauci-bacillary in nature, which often gives a negative result in routine techniques, such as culture and staining for acid-fast bacilli (AFB).…”

Section: Discussionmentioning

confidence: 99%

“…[7][8][9] Incidence of GI TB is 3% of all extrapulmonary TB, and involvement of the appendix is rare, occurring in only 0.1-3% of GI TB cases. 8,10,11 Appendicular TB is commonly found in young adults with the average age of 30 years old with a greater incidence in women. 12 The presentation of appendicular TB can be similar to appendicitis.…”

Section: Case Reportmentioning

confidence: 99%

Appendicular Tuberculosis as Manifestation of Gastrointestinal Tuberculosis: A Case Report

Yuliza

Rosyid

Effendi

et al. 2021

View full text Add to dashboard Cite

Introduction: Gastrointestinal tuberculosis (GI TB) is quite rare with 3% incidence of all extrapulmonary involvement. Appendicular TB may occur in 0.1 - 3% of cases. Diagnosis is often difficult because the patient usually complains about chronic abdominal pain and fever. A definite diagnosis is based on histopathological examination of resected specimens from the appendectomy procedure.Case: We present a 37-year-old male patient admitted to the hospital with chronic abdominal pain, fever, nausea, and loss of body weight. The patient never had a persistent cough, hemoptysis, or night sweating. Physical examination showed pain and muscular rigidity in the right iliac area during palpation with Blumberg's sign and Rovsing's sign positive. Abdomen ultrasound imaging showed an appendicular abscess. The patient underwent appendectomy afterwards with histopathology result showing TB. The patient was treated with first category anti-tuberculosis drugs (ATD).Discussion: Diagnosis of appendicular TB is difficult due to unspecific clinical presentations. Appendicular TB patients often complain of signs and symptoms which are similar to acute appendicitis. These conditions can delay ATD treatment because the definitive diagnosis could be made after histopathological examination.Summary: Appendicular TB is a rare case of extrapulmonary TB. It can present as acute appendicitis. The definitive diagnosis is based on the histopathological examination. It is recommended to check the appendicectomy specimens histopathologically to exclude TB or other diseases.

show abstract

Appendicular tuberculosis: a less encountered clinical entity

Cited by 5 publications

References 7 publications

Mycobacterium bovisinfection of the appendix: a case of appendiceal tuberculosis in rural England

Mycobacterium bovisinfection of the appendix: a case of appendiceal tuberculosis in rural England

A Rare Case of Tuberculosis Revealed by Acute Appendicitis: A Case Report

Appendicular Tuberculosis as Manifestation of Gastrointestinal Tuberculosis: A Case Report

Contact Info

Product

Resources

About