Appendicular agenesis: a case report

Abstract

Congenital agenesis or absence of vermiform appendix is very rare. Herein, author reported a case of a 28 years old Vietnamese lady who presented with a picture of acute appendicitis. During surgery, author failed to find the appendix. Postoperatively, she made uneventful recovery and she was diagnosed as a case of nonspecific abdominal pain (NSAP) with appendicular agenesis.

A rare case of situs inversus totalis associated with sigmoid diverticulitis and appendicular agenesis. Embryological, clinical considerations and literature review

“…Embryologically, the vermiform appendix is formed around the 10 th week of pregnancy from the caecum as a tubular end-capped structure. Appendicular atresia known causes can be an intrauterine vascular accident or auto-amputations due to an intrauterine fibrous band [ 12 ]. Also, a developmental defect called the apple peel jejunal atresia (autosomal recessive transmission) and associated with short midgut syndrome can cause appendicular atresia.…”

“…Agenesis of the vermiform appendix may be isolated or may be part of a complex of ileo-cecal malformations. Collins studied this aspect and made the following classification: type I – absence of appendix and cecum; type II – rudimentary cecum and absence of appendix; type III – normal cecum and absence of appendix; type IV – normal cecum and rudimentary appendix; type V – giant cecum and absence of appendix [ 12 , 13 , 14 ]. The presented case is a type III.…”

Appendicular agenesis as an unusual intraoperative finding in acute abdomen: Case report and literature review

“…Failure in the appendix development according to Hei et al, could be attributed to an intrauterine vascular accident, and in some cases is associated with intestinal atresia [12] , as well, toxic-associated with Thalidomide are described in literature as possible causes of appendix abnormalities [13] . Literature case reports of appendiceal absence are usually described in adult patients [1] , [2] , [3] , [4] , [5] , [6] , [7] , [8] , [9] , [10] . There are no clinical manifestations of appendix agenesis, and usually are found in patients with acute abdomen suspicion that needs laparotomy, as in our case; following a systematic review of the cavity, no appendix were found.…”

“…First description of appendicular agenesis was made by Morgani et al [1] , incidence is approximately 1:100.000 laparotomies due to acute abdomen according to Chevre et al [2] , [3] . Non-specific causes of acute abdomen are usually due to acute appendicitis [2] , and diagnosis of appendicular agenesis are frequently performed in an incidental way [4] . Abnormalities of the appendix are unusual, and frequently there are not found because they do not show any signs or symptoms [2] , [3] , [4] .…”

“…Non-specific causes of acute abdomen are usually due to acute appendicitis [2] , and diagnosis of appendicular agenesis are frequently performed in an incidental way [4] . Abnormalities of the appendix are unusual, and frequently there are not found because they do not show any signs or symptoms [2] , [3] , [4] .…”