Apparent interruption of atrial conduction pathways after surgical repair of transposition of great arteries

Isaacson, Ronald; Titus, Jack L.; Merideth, John; Feldt, Robert

doi:10.1016/0002-9149(72)90044-6

Cited by 83 publications

(12 citation statements)

References 10 publications

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“…The precise course of the artery of supply to the node is also not fully understood, James (1961) indicating that it may approach the node in either a clockwise or counterclockwise fashion relative to the superior vena cava, while Hutchinson (1978) has described a caval circle of arteries in the environs of the node. ' These possible variations are of major significance in postoperative sinus node dysfunction, a problem compounded by controversies surrounding the substrates for internodal atrial conduction (James, 1963;El Said et al, 1972;Isaacson et al, 1972;Janse and Anderson, 1974). With all these considerations in mind, we have attempted to define accurately the anatomy, disposition, connections, and vascular supply of the sinuatrial node by reconstructions from histological sections of 25 normal human infant hearts.…”

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confidence: 99%

Location and vascular supply of sinus node in human heart.

Anderson¹,

Ho²,

Anderson³

1979

Heart

147

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The exact location of the sinus node was determined in 25 infant hearts using reconstructive techniques. The sinus node was found to lie on the lateral aspect of the superior cavo-atrial junction in the great majority (22 hearts). In only 3 hearts was it found to straddle the summit of the crest of the right atrial appendage where it is popularly believed to be located. In the majority of instances a single artery supplied the node (in 11 hearts the artery approached posteriorly, and in 10 the artery approached anteriorly), though there was considerable variation in the exact anatomy of the arterial supply. Connections between the sinus node and atrial myocardium were diffuse and abundant but in no instances were tracts of specialised cells observed leaving the node and traversing any distance through the atrial wall. These findings are relevant to the sinus node dysfunction that may follow cardiac surgical procedures.

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mentioning

confidence: 99%

Location and vascular supply of sinus node in human heart.

Anderson¹,

Ho²,

Anderson³

1979

Heart

147

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“…Varying atrial dysrhythmias of the sick sinus syndrome after surgical closure of atrial septal defects (Young, AIRIALriou BRI L sic .n -Said et al, 1972) have been reported, but symptoms and treatment were not discussed. Deaths have been attributed to the dysrhythmias and careful studies have been made of the sinus node and atrial myocardium (Kaplan et al, 1973;El-Said et al, 1972;Isaacson et al, 1972;Hudson, 1967). Sinus node damage has been confirmed histologically.…”

Section: Discussionmentioning

confidence: 99%