“…They observed a reduction in the total cellular content 6f the spleen of mice treated with cortisone. Stephens et al (197) described a striking in crease in the urinary excretion of free histidine in patients medicated with ACTH or cortisone, a phenomenon which previously had been observed only in connection with clinical remission of rhemuatoid arthritis.…”
“…They observed a reduction in the total cellular content 6f the spleen of mice treated with cortisone. Stephens et al (197) described a striking in crease in the urinary excretion of free histidine in patients medicated with ACTH or cortisone, a phenomenon which previously had been observed only in connection with clinical remission of rhemuatoid arthritis.…”
“…Tyrosinuria in pregnancy has been reported by Lawrie (5). Because pregnancy often produces clinical remissions in rheumatoid arthritis, and because it has been reported that remissions produced with adrenocorticotrophic hormone and 17-hydroxy-11-dehydrocorticosterone result in increased excretion of histidine (6) and other amino acids (7), it was thought worthwhile to investigate the aminoaciduria of pregnancy. This paper reports the urinary excretion of 14 amino acids measured microbiologically.…”
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