2001
DOI: 10.1074/jbc.m006222200
|View full text |Cite
|
Sign up to set email alerts
|

Apoptosis-resistant Mitochondria in T Cells Selected for Resistance to Fas Signaling

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
30
0

Year Published

2001
2001
2011
2011

Publication Types

Select...
6
1
1

Relationship

0
8

Authors

Journals

citations
Cited by 34 publications
(30 citation statements)
references
References 56 publications
0
30
0
Order By: Relevance
“…For example, cells selected for resistance to Fas were completely cross-resistant to VP-16 or staurosporin (20). However, our TRAIL-resistant clones were not cross-resistant to either Fas or chemotherapeutic drugs such as paclitaxel.…”
Section: Discussionmentioning
confidence: 96%
See 2 more Smart Citations
“…For example, cells selected for resistance to Fas were completely cross-resistant to VP-16 or staurosporin (20). However, our TRAIL-resistant clones were not cross-resistant to either Fas or chemotherapeutic drugs such as paclitaxel.…”
Section: Discussionmentioning
confidence: 96%
“…All of them showed similar resistance to TRAIL as their parental clone R4 (data not shown). It has been reported that in vitro selection for resistance to some apoptosisinducing stimuli may result in cross-resistance to other cytotoxic agents (20,22). To determine whether our resistant clones also co-selected for resistance to Fas and paclitaxel, the parental SW480 cells and the resistant clones R4, R6, and R10 were treated with TRAIL, Fas, or paclitaxel.…”
Section: Trail-resistant Sw480 Colon Cancer Cells Selected After Prolmentioning
confidence: 99%
See 1 more Smart Citation
“…Our data also showed that Naph induced apoptosis by increasing DNA fragmentation, nuclear condensation, and cell morphological changes by DAPI staining. In the process of apoptosis, caspases have been reported to be activated via both the extrinsic and intrinsic cell death pathways (20,21). In particular, the activation of caspase-3 is commonly involved in the apoptosis process in various cell types.…”
Section: Discussionmentioning
confidence: 99%
“…It also contributes to resistance of GBM to therapy and leads to escape of tumor cells from surveillance by the immune system [115]. During apoptosis, caspases are activated to cleavage cellular substrates and lead to biochemical and morphological changes that are characteristics of apoptosis [116,117]. There are two major pathways by which caspase activation occurs: via the extrinsic pathways and the intrinsic pathway.…”
Section: Apoptosis and Bim In Glioblastomamentioning
confidence: 99%