Abstract:National audienceSubcutaneous infusion with apomorphine is one of the treatments available for Parkinson's disease. Even if increasing evidence of its efficacy on both motor and non-motor symptoms is found in the literature, it is still underused. This article reviews pharmacological and pharmacokinetic properties of apomorphine and its impact on clinical decision making. Despite their complexity, those properties are a key to understanding the effect of the drug and its variability of efficacy and dosage amon… Show more
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