Apolipoprotein B and A-I distribution in Mexican urban adults: Results of a nationwide survey

Valles, Victoria; Aguilar-Salinas, Carlos A.; rez, Francisco J. G; Rojas, Rosalba; Franco, Aurora; Oláiz, Gustavo; Rull, Juan; Sepúlveda, Jaime

doi:10.1053/meta.2002.31977

Cited by 21 publications

(14 citation statements)

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“…The demographic data and medical history were recorded using a standardized questionnaire utilized in previous nationwide Mexican surveys (11)(12)(13)(14). It included questions on tobacco use, alcohol consumption, accidents, family history, diabetes, hypertension, and other chronic disorders.…”

Section: Methodsmentioning

confidence: 99%

Characteristics of Patients With Type 2 Diabetes in México

Monroy²,

et al. 2003

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OBJECTIVE -To describe the clinical characteristics of the diabetic population that formed part of a population-based survey conducted in México.RESEARCH DESIGN AND METHODS -In 2000, information was obtained from 42,886 subjects aged Ն20 years using a multistage sampling procedure. Standardized questionnaires were used. Anthropometric measurements, blood pressure, and capillary glucose concentrations were taken.RESULTS -Type 2 diabetes was found in 3,597 subjects (age-adjusted prevalence 8.18%), of which 2,878 (80%) had previously been diagnosed. The average age of the diabetic participants was 55.2 Ϯ 13.5 years; 13% were Ͻ40 years of age. Nine percent had been diagnosed for Ͼ10 years. The average BMI was 29.2 Ϯ 5.7 kg/m 2 ; three-quarters of the cases had BMI Ͼ25 kg/m 2 . The average waist circumference was 102 Ϯ 13.4 cm, and increased waist circumference was more common among women. Arterial hypertension was found in half of the cases and, of those on treatment, only one-third had a blood pressure Ͻ140/90 mmHg. Smoking was reported in 34% of the diabetic group, a higher rate than in the nondiabetic subjects. There was at least one modifiable coronary risk factor in 67.6% of the cases. Very few followed an exercise or dietary regimen and a small percentage used insulin.CONCLUSIONS -Diabetes affects a large proportion of Mexican adults (8.18%). This figure may be underestimated. The majority of the subjects had modifiable risk factors for the chronic complications of diabetes. Only a few achieved adequate blood pressure control and other treatment goals.

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Section: Methodsmentioning

confidence: 99%

Characteristics of Patients With Type 2 Diabetes in México

Monroy²,

et al. 2003

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“…Figure 1A shows the reported apo AI median values from the 64 published studies considered acceptable. In adults, the range is at least two-fold for the majority 83 Reference intervals from published studies. The bars represent the interval between the 2.5th and 97.5th centile for each study with the number of subjects above the bar.…”

Section: Number Of Studies Available For Analysismentioning

confidence: 99%

“…Only six stated categorically that the subjects were only Caucasian (14,40,57,58,60,78,79). Three reported results in both Caucasian and black African Americans without distinction (18,19,81); three gave data on blacks and Caucasians separately (84)(85)(86); one reported on a large cohort of Caucasians, blacks, and Hispanic individuals (58); one reported on black Africans; two described values for restricted ethnic groups (42,44,83,87); and seven reported on Asians (28,29,43,63,65,75,77). The remaining 58 did not provide racial composition of their study subjects.…”

Section: Ethnic Group-specific Reference Intervalsmentioning

confidence: 99%

Reference distributions for apolipoproteins AI and B and B/AI ratios: comparison of a large cohort to the world's literature

Ritchie

Palomaki

Neveux

et al. 2006

Clinical Laboratory Analysis

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Limiting the clinical utility of apolipoproteins AI (apo AI) and B (apo B) and the apo B/AI ratios until the last decade has been the lack of satisfactory methods for quantifying serum levels and credible reference materials. Great technological strides have been made in the last few years. The remaining barrier to more relevant and cost-effective use of serum protein data for diagnosis and prognosis has been the availability of widely recognized reliable reference intervals from birth to old age for both males and females. A total of 82 publications reporting reference intervals have been identified that meet most of the same inclusion criteria used in our prior six studies. These have been analyzed statistically and compared to similar studies, i.e., sufficient number, listed subject criteria, method, and reference material, in general terms. Published smaller studies with constrained age ranges, agree on average with our large series of life-long reference intervals that range from less than one year to over 80 years. This study was performed to assess the degree of agreement between smaller reference interval studies to our large population analysis. This meta-analysis provides support and reassurance that many of the smaller reference intervals published previously fall within reasonable limits of out large population.

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“…BMI was used instead of waist circumference because only the distribution of the former was available (National Survey of Chronic Diseases 1992-1993) (15)(16)(17)(18). Our definition is based on the decile distribution of the variables: 1 point is given per decile.…”

Section: Methodsmentioning

confidence: 99%

Design and Validation of a Population-Based Definition of the Metabolic Syndrome

Aguilar-Salinas

Rojas

González‐Villalpando³

et al. 2006

Diabetes Care

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OBJECTIVE -The National Cholesterol Education Program (NCEP) definition of the metabolic syndrome was modified to be described as a continuous variable and adapted to the characteristics of a Hispanic population.RESEARCH DESIGN AND METHODS -Age/sex population percentiles for every component of the NCEP criteria were included in this approach using population-based data from a Mexican nationwide survey (2,158 subjects). One point was given per decile for every component. The total number of points accumulated was used to classify subjects. The predictive power for incident diabetes was evaluated using the 7-year follow-up results of the Mexico City Diabetes Study.RESULTS -Our population-based method had a significantly better prognostic power compared with the original and the updated NCEP definitions (area under the receiver operating characteristic curve 0.746 vs. 0.697 and 0.723, respectively, P Ͻ 0.05). Using individuals with Յ1 component of the NCEP definition as reference, the odds ratio was greater in the upper quartile of the points scale (Ն39 points) (12.71 [95% CI 5.67-28.49]) compared with that calculated for the original (9.52 [4.69 -19.31]) and the updated (11.14 [5.33-23.30]) NCEP criteria. The major advantage of our approach is the detection of subjects at the extremes of the range of diabetes risk and the ability to estimate this risk as a continuum.CONCLUSIONS -Our method adapts the NCEP criteria to the characteristics of a Hispanic population. It improves the predictive power of the NCEP criteria for future diabetes.

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Apolipoprotein B and A-I distribution in Mexican urban adults: Results of a nationwide survey

Cited by 21 publications

References 0 publications

Characteristics of Patients With Type 2 Diabetes in México

Characteristics of Patients With Type 2 Diabetes in México

Reference distributions for apolipoproteins AI and B and B/AI ratios: comparison of a large cohort to the world's literature

Design and Validation of a Population-Based Definition of the Metabolic Syndrome

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