Aplicabilidade clínica da técnica de sequenciamento de nova geração com enfoque em displasias esqueléticas

Fatores de susceptibilidade às fissuras orofaciais

“…Rare variants (minor allele frequency <0.5%) were prioritized according to frequencies in public databases (1000 Genomes We also removed variants presenting strand bias, i.e., variants which read are mapped preferentially to forward or reverse strand, according to (Yamamoto, 2017).…”