Apheresis activity in Spain: A survey of the Spanish Apheresis Group

Optia® continuous mononuclear collection (CMNC) system is a safe and efficient system for hematopoietic progenitor cells‐apheresis (HPC‐a) collection and yields a lower product hematocrit (HCT%) than the COBE® spectra system: A retrospective study

“…The COBE® Spectra apheresis system (Terumo BCT, Lakewood, Colorado) has been the most widely used platform for many years for HPC collection . The Spectra Optia® apheresis system (Terumo BCT, Lakewood, Colorado) is a newer system with several upgrades including an automated interface management system that automatically detects and maintains buffy coat interface for HPC collection .…”

Continuous CD34+ cell collection by a new device is safe and more efficient than by a standard collection procedure: results of a two‐center, crossover, randomized trial

“…The COBE Spectra (COBE; TerumoBCT) has been the most widely used platform to collect HSCs worldwide . The COBE supports both dual‐step and single‐step mononuclear cell (MNC) processing, but is being replaced by the Spectra Optia (OPTIA; TerumoBCT), which previously supported only dual‐step MNC processing.…”

Comparison of plasma exchange procedures using three apheresis systems

“…Plasma exchange (PE) is a therapeutic procedure in which blood of the patient is passed through a medical device which separates out plasma from other components of blood, the plasma is removed and replaced with a replacement solution . PE is the most commonly performed therapeutic apheresis procedure, according to data from international registries and national surveys . The basic premise of PE is that removal of substances will reduce further damage and may permit reversal of the pathologic process .…”