Aphasia Resulting From Occlusion of the Left Anterior Cerebral Artery

Racy, Anis

doi:10.1001/archneur.1979.00500400075012

Cited by 35 publications

(3 citation statements)

References 10 publications

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“…Our finding that lesions in the supramarginal cortex, superior temporal gyrus, insula, and SLF were associated with a low AQ score in patients with stroke is consistent with that of previous studies. A previous case report wrote that the Rolandic cortex is the cause of transcortical motor aphasia (30), the Heschl's gyrus is involved in the comprehension of syntax (31), and posterior corona radiata lesions are associated with poor recovery from aphasia (32). These lesions had not been considered as the main cause for aphasia (8).…”

Section: Discussionmentioning

confidence: 99%

Association of Lesion Location With Long-Term Recovery in Post-stroke Aphasia and Language Deficits

et al. 2019

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Background: Recovery from post-stroke aphasia is important for performing the activities of daily life, returning to work, and quality of life. We investigated the association between specific brain lesions and the long-term outcome of four dimensions of aphasia: fluency, comprehension, naming, and repetition 12 months after onset in patients with stroke. Methods: Our retrospective cross-sectional observational study investigated the relationship between the Korean version of the Western Aphasia Battery scores in 31 stroke patients 1 year after the onset of stroke and stroke lesion location. Brain lesions were assessed using voxel-based lesion symptom mapping (VLSM) in conjunction with magnetic resonance imaging. Results: Damage to the Rolandic cortex, Heschl's gyrus, the posterior corona radiata, supramarginal cortex, superior longitudinal fasciculus, superior temporal gyrus, and insula was associated with a low total AQ score. Lesions in the inferior triangularis and inferior operculum of the frontal cortex, supramarginal cortex, and insula were associated with a poor fluency outcome. Damage to the parietal cortex, angular cortex, temporal middle cortex, sagittal stratum, and temporal superior cortex was associated with poor recovery of comprehension skills. Lesions in the angular cortex, supramarginal cortex, posterior corona radiata, superior longitudinal fasciculus, internal capsule, temporal superior cortex, and temporal middle cortex were associated with poor recovery of naming in patients with stroke. Damage to the superior temporal cortex, posterior corona radiata, and superior longitudinal fasciculus was associated with poor recovery of repetition component. Conclusions: We identified specific brain lesions associated with long-term outcomes in four dimensions of aphasia, in patients with post-stroke aphasia. Our findings may be useful for advancing understanding for the pathophysiology of aphasia in stroke patients.

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Section: Discussionmentioning

confidence: 99%

Association of Lesion Location With Long-Term Recovery in Post-stroke Aphasia and Language Deficits

et al. 2019

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“…Effects of lesions of the SMA in humans. Damage to the SMA in patients has been reported to produce effects on speech as well as on limb movement (Alexander & Schmitt 1980;Goldberg, Mayer & Toglia 1981;Jonas 1981;Kornyey 1975;Masdeu, Schoene & Funkenstein 1978;Racy, Janotta & Lehner 1979;Rubens 1975). The effects on speech are usually observed with damage to the dominant left hemisphere although an exception has been reported (Brust, Plank, Burke, Guobadia & Healton 1982).…”

Section: 2mentioning

confidence: 99%

Supplementary motor area structure and function: Review and hypotheses

1985

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Though its existence has been known for well over 30 years, only recently has the supplementary motor area (SMA) and its role in the cortical organization of movement come to be examined in detail by neuroscientists. Evidence from a wide variety of investigational perspectives is reviewed in an attempt to synthesize a conceptual framework for understanding SMA function. It is suggested that the SMA has an important role to play in the intentional process whereby internal context influences the elaboration of action. It may be viewed as phylogenetically older motor cortex, derived from anterior cingulate periarchicortical limbic cortex, which, as a key part of a medial premotor system, is crucial in the "programming" and fluent execution of extended action sequences which are "projectional" in that they rely on model-based prediction. This medial system can be distinguished from a lateral premotor system postulated to have evolved over phylogeny from a different neural source. An anatomico-physiologic model of the medial premotor system is proposed which embodies the principles of cyclicity and reentrance in the process of selecting those neural components to become active in conjunction with the performance of a particular action. The postulated dynamic action of this model in the microgenesis of a discrete action is outlined. It is concluded that although there is a great deal to be learned about the SMA, a convergence of current evidence can be identified. Such evidence suggests that the SMA plays an important role in the development of the intention-to-act and the specification and elaboration of action through its mediation between medial limbic cortex and primary motor cortex.

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“…The relationship between left frontal lobe lesions and comprehension deficits in particular is still uncertain. Regarding the former point, although left frontal lobe lesions are generally known to produce nonfluent aphasia such as Broca'a aphasia [9], aphemia (or pure anarthria [18] or apraxia of speech [35]), transcortical motor aphasia and supplementary motor area aphasia [6], the critical lesion producing speech nonfluency has been much debated [1,2,13,17,19,21,24,26,28,37]. It has become clear that Broca's aphasia develops only following lesions extending beyond Broca's area; lesions restricted to Broca's area alone do not usually cause nonfluency or persistent speech disorders [2,13,24,25,32,36].…”

Section: Introductionmentioning

confidence: 99%

Transcortical sensory aphasia following left frontal infarction

Otsuki

Soma

Koyama

et al. 1998

Journal of Neurology

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Two right-handed patients who exhibited language disability after left frontal infarction are described. The patients spoke fluently and exhibited excellent repetition ability from the onset of infarction without exhibiting any oral apraxia, but had deficits in auditory comprehension, naming, reading and writing. In both patients, brain magnetic resonance imaging (MRI) revealed infarction in the left inferior frontal gyrus, the middle frontal gyrus and the anterior part of the lower precentral gyrus. Single photon emission computed tomography (SPECT) revealed decreased blood flow in the same regions as those shown to be infarcted by MRI. The MRI and SPECT findings and the symptoms of these patients suggest that left frontal lesions that encompass Broca's area produce fluent aphasia if the posterior part of the left precentral gyrus or motor cortex remains intact and that lesions anterior to Broca's area and the middle frontal gyrus produce a deficit in auditory comprehension of single words as well as sentences.

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Aphasia Resulting From Occlusion of the Left Anterior Cerebral Artery

Cited by 35 publications

References 10 publications

Association of Lesion Location With Long-Term Recovery in Post-stroke Aphasia and Language Deficits

Association of Lesion Location With Long-Term Recovery in Post-stroke Aphasia and Language Deficits

Supplementary motor area structure and function: Review and hypotheses

Transcortical sensory aphasia following left frontal infarction

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