Apexification with calcium hydroxide and mineral trioxide aggregate: Report of two cases

Gawthaman, Murugesan; Vinodh, Selvaraj; Mathian, Veerabadhran Mahesh; Vijayaraghavan, Rangasamy; Karunakaran, Ramachandran

doi:10.4103/0975-7406.114305

Cited by 19 publications

(12 citation statements)

References 7 publications

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“…REPs began around 1952, when a German dentist called: Dr. B. W. Hermann advocated the use of calcium hydroxide as a dressing for after a vital pulp amputation (Hermann, 1952 ). Today, many dentists still use calcium hydroxide, mainly for apexification (Gawthaman et al, 2013 ), although MTA has overtaken calcium hydroxide to become the most popular pulp repair material (Monteiro et al, 2017 ). Subsequent REPs include the development of guided tissue or bone regeneration procedures and distraction osteogenesis (Jani, 1975 ); the application of platelet rich plasma (PRP) for bone augmentation (Kassolis et al, 2000 ); the use of platelet rich fibrin (PRF) for periodontal wound healing (Powell et al, 2009 ); and blood clot revascularization (BCR) by a Norwedgian dentist called Dr. Nygaard-Ostby for the regeneration of tissues within the root canals of pulpotimized teeth (Ostby, 1961 ; Nygaard-Ostby and Hjortdal, 1971 ).…”

Section: Introductionmentioning

confidence: 99%

Platelet-Rich Plasma and Platelet-Rich Fibrin Can Induce Apical Closure More Frequently Than Blood-Clot Revascularization for the Regeneration of Immature Permanent Teeth: A Meta-Analysis of Clinical Efficacy

Murray

2018

Front. Bioeng. Biotechnol.

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The purpose of this review was to compare the clinical efficacy of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), vs. blood clot revascularization (BCR) for the regeneration of immature permanent teeth. A survey of the literature identified 222 cases of immature permanent teeth which had been given PRP, PRF or BCR regeneration treatment with at least a year-long follow-up in 12 different articles. A meta-analysis of the 222 immature permanent teeth after 1 year, were compared to assess the ability of PRP, PRF, and BCR to accomplish apical closure, a periapical lesion healing response, root lengthening, and dentinal wall thickening. The mean success rate for apical closure or reduction after 1 year was: PRP (85.1%) PRF (85.2%), and BCR (58.8%). The mean success rate for root lengthening after 1 year was: BCR (64.1%), PRP (64.2%), and PRF (74.1%). The periapical lesion healing response was 88.9% for BCR, 100% for PRP, and 100% for PRF. Dentinal wall thickening was 100% for BCR, 100% for PRP, and 100% for PRF. Apical closure occurred more frequently following PRP and PRF than with BCR (Fischer test, P < 0.0011), for all the other effects the PRP, PRF, and BCR treatments were similarly effective (Fischer tests, P > 0.05). In conclusion, the fractured or decayed immature permanent teeth of children and young adults aged 6 years to 28 which have a restorable crown, but thin dentinal walls may be regenerated by using a revascularization procedure which draws blood and stem cells into a disinfected root canal space. Although BCR is most common revascularization method, apical closure may occur more frequently if PRF and PRP are used instead of BCR for the regeneration of immature permanent teeth. The proper use of regenerative procedures can be very successful at the disinfection of bacteria from the periapical region of immature permanent teeth, which helps to heal localized lesions, and avoid the need for complex apical surgery, in addition to regenerating tissues to strengthen the structure of immature teeth, to help prevent tooth fracture and tooth loss.

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Section: Introductionmentioning

confidence: 99%

Platelet-Rich Plasma and Platelet-Rich Fibrin Can Induce Apical Closure More Frequently Than Blood-Clot Revascularization for the Regeneration of Immature Permanent Teeth: A Meta-Analysis of Clinical Efficacy

Murray

2018

Front. Bioeng. Biotechnol.

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“…Mineral trioxide aggregate (MTA) has been used as apical plug in non-vital teeth with incompletely formed roots ( 1 , 2 ). In this situation, the marginal sealing provided by MTA is better compared to other materials ( 3 , 4 ), and ex vivo studies have demonstrated improvement when the cement remains in contact with the phosphate buffered saline (PBS) ( 5 , 6 ) due to the formation of carbonate apatite at the cement-dentin interface ( 7 ), with tag-like structures which partially obliterates the spaces between material and dentin ( 5 ).…”

Section: Introductionmentioning

confidence: 99%

Analysis of sealing ability of endodontic cements apical plugs

et al. 2018

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BackgroundIt is unknown whether the bioactivity of Biodentine characterized by the precipitation of hydroxyapatite and formation of tags into the dentinal tubules improve its sealing ability as an apical plug. Aim: To evaluate the sealing ability provided by Biodentine and mineral trioxide aggregate (MTA) apical plugs, with or without phosphate-buffered saline (PBS) intracanal dressing, using a glucose leakage method.Material and MethodsThe space of the canal of 100 root segments with about 12 mm long was shaped using Gates-Glidden. After created an apical retrograde cavity, the root segments were randomly divided into 4 groups (n = 25): G1 – Biodentine; G2 - Biodentine + PBS intracanal dressing; G3 - MTA and G4 - MTA + PBS intracanal dressing. All access openings were filled with temporary cement and all root segments were introduced in floral foams moistened with PBS. After 2 months, all root segments were prepared to evaluate the glucose leakage. The amount of glucose leakage was quantified by a spectrophotometer and the data were analyzed using chi-square test (p<0.05).ResultsTraces of the glucose were observed in a higher of samples that received Biodentine apical plug (p<0.05). The exposure to intracanal PBS did not influence the sealing provided by Biodentine and MTA.ConclusionsThe Biodentine had lower sealing ability than MTA. The interaction with PBS intracanal dressing did not improve the sealing ability provided by sealers. Key words:Apexification, dental cements, dental leakage, glucose, pressure.

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“…Most of our participants had large dental fillings that often included the root canals of permanent teeth. Considering the type of treatment intervention in such cases, i.e., apexogenesis or apexification, the closure of the apex before the predicted time is expected [24,25]. Therefore, in our study, the filled permanent teeth had already reached the final stage of development (stage 8), according to the DPR images.…”

Section: Discussionmentioning

confidence: 82%

Does dental caries affect dental development in children and adolescents?

Dhamo

Elezi

Kragt

et al. 2018

Bosn J of Basic Med Sci

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Although a link between dietary changes, caries, and dental development has been observed, the literature provides little insight about this relationship. The aim of our study was to investigate the association between dental caries and dental development in a clinical sample of Albanian children and adolescents. In total, 118 children and adolescents, born between 1995 and 2004 and aged 6-15 years, were included. Dental caries in the deciduous dentition was assessed using the Decayed, Filled Teeth (dft) index and dental caries in the permanent dentition was assessed using the Decayed, Missing, Filled Teeth (DMFT) index. Dental development during the permanent dentition was determined using the Demirjian method. Linear and ordinal regression models were applied to analyze the associations of dental caries with dental age and developmental stages of each left mandibular tooth. Dental caries in the deciduous dentition, estimated as a median dft of 2.0 (90% range, 0.0-9.1), was significantly associated with lower dental age (β = -0.21; 90% CI: -0.29, -0.12) and with delayed development of the canine, both premolars, and the second molar. Untreated dental caries (dt) was associated with lower dental age (β = -0.19; 90% CI: -0.28, -0.10). Dental caries in the permanent dentition, estimated as a median DMFT of 1.0 (90% range, 0.0-8.0), was not significantly associated with dental age (β = 0.05; 90% CI: -0.04, 0.14). However, the DMFT was associated with the advanced stages of development of both premolars and the second molar. The untreated dental caries in the deciduous dentition delays the development of permanent teeth.

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Apexification with calcium hydroxide and mineral trioxide aggregate: Report of two cases

Cited by 19 publications

References 7 publications

Platelet-Rich Plasma and Platelet-Rich Fibrin Can Induce Apical Closure More Frequently Than Blood-Clot Revascularization for the Regeneration of Immature Permanent Teeth: A Meta-Analysis of Clinical Efficacy

Platelet-Rich Plasma and Platelet-Rich Fibrin Can Induce Apical Closure More Frequently Than Blood-Clot Revascularization for the Regeneration of Immature Permanent Teeth: A Meta-Analysis of Clinical Efficacy

Analysis of sealing ability of endodontic cements apical plugs

Does dental caries affect dental development in children and adolescents?

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