APAP device technology and correlation with patient compliance

Netzel, Thomas; Hein, H.; Hein, Ye Myat

doi:10.1007/s11818-014-0662-0

Cited by 6 publications

(3 citation statements)

References 7 publications

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“…Bench studies have been proposed to evaluate the responses of APAP devices in different conditions, such as the presence of predefined sleep disordered breathing (SDB) patterns and air leak, [18][19][20][21][22][23][24][25] whereas no such study to date has focused on pressure-relief CPAPs and APAPs. We investigated seven pressure-relief features developed by three CPAP device manufacturers with a previously reported bench model.…”

Section: 17mentioning

confidence: 99%

Pressure-Relief Features of Fixed and Autotitrating Continuous Positive Airway Pressure May Impair Their Efficacy: Evaluation with a Respiratory Bench Model

Zhu

Aouf

Roisman

et al. 2016

Journal of Clinical Sleep Medicine

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Section: 17mentioning

confidence: 99%

Pressure-Relief Features of Fixed and Autotitrating Continuous Positive Airway Pressure May Impair Their Efficacy: Evaluation with a Respiratory Bench Model

Zhu

Aouf

Roisman

et al. 2016

Journal of Clinical Sleep Medicine

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“…Erfahrungen der Schlafmediziner im Rahmen der Umversorgung in Folge von Ausschreibungen (Gerätetausch durch den Ausschreibungsgewinner) haben gezeigt, dass viele Patienten mit einem veränderten Regel-Algorithmus nicht zurechtkommen (9). Die gleichen Probleme könnten auch bei der Versorgung mit Klinikgeräten entstehen.…”

Section: /2016 221 Tipps Für Die Praxisunclassified

Patientengeräte in einer Gesundheitseinrichtung

Reents¹,

Wagner²

2016

Schlaf

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Zunehmend kommt es vor, dass Patienten ärztlich verordnete aktive Homecare-Medizinprodukte in eine Gesundheitseinrichtung mitbringen, z.B. Schlafapnoe-Atemtherapiegeräte, Beatmungsgeräte, Insulinpumpen, Insulin-Pen, Schmerzmittelpumpen, Tens-Geräte, Geräte zur Inhalationstherapie. Der folgende Beitrag soll am Beispiel der MP zur Behandlung von Schlafatmungsstörungen (Positiv drucktherapie) die bestehenden Probleme beschreiben und eine mögliche rechtssichere Lösung zur Diskussion stellen.

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“…An issue of concern that arises from these observations is that if patients exhibiting NED actually have different upper airway physiology or exhibit upper airway muscle dysfunction, would they require different positive-pressure devices or electrical stimulation modalities than currently available. It also follows that bench tests used to evaluate CPAP devices based on the Starling resistor model would not apply to all patients (1,6,17,22,38). Recently, Lambeth et al (20) published a paper that observed NED within a collapsible tube model using a unidirectional flow source.…”

Section: Introductionmentioning

confidence: 99%

Mimicking a flow-limited human upper airway using a collapsible tube: relationships between flow patterns and pressures in a respiratory model

Zhu

Farré

Katz

et al. 2018

Journal of Applied Physiology

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The upper airway (UA) in humans is commonly modeled as a Starling resistor. However, negative effort dependence (NED) observed in some patients with obstructive sleep apnea (OSA) contradicts predictions based on the Starling resistor model in which inspiratory flow is independent of inspiratory driving pressure when flow is limited. In a respiratory bench model consisting of a collapsible tube and an active lung model (ASL5000), inspiratory flow characteristics were investigated in relation to upstream, downstream, and extra-luminal pressures (denoted as P, P, and P, respectively) by varying inspiratory effort (muscle pressure) from -1 to -20 cmHO in the active lung. P was provided by a constant airway pressure device and varied from 4 to 20 cmHO, and P was set at 10 and 15 cmHO. Upstream resistance at onset of flow limitation and critical transmural pressure (P) corresponding to opening of the UA were found to be independent of P, P, and P. With fixed P, when P fell below a specific value (P'), inspiratory peak flow became constant and independent of P. NED plateau flow patterns at mid-inspiration (V̇) were produced within the current bench setting when P fell below P'. V̇ was proportional to P, and the slope (ΔV̇/ΔP) increased linearly with P. P and P were the two final independent determinants of inspiratory flow. Our bench model closely mimics a flow-limited human UA, and the findings have implications for OSA treatment and research, especially for bench-testing auto-titrating devices in a more physiological way. NEW & NOTEWORTHY A respiratory model consisting of a collapsible tube was used to mimic a flow-limited human upper airway. Flow-limited breathing patterns including negative effort dependence were produced. Transmural and downstream pressures acting on the tube are the two independent determinants of the resulting inspiratory flow during flow limitation. The findings have implications for obstructive sleep apnea treatment and research, especially for bench-testing auto-titrating devices in a more physiological way.

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APAP device technology and correlation with patient compliance

Cited by 6 publications

References 7 publications

Pressure-Relief Features of Fixed and Autotitrating Continuous Positive Airway Pressure May Impair Their Efficacy: Evaluation with a Respiratory Bench Model

Pressure-Relief Features of Fixed and Autotitrating Continuous Positive Airway Pressure May Impair Their Efficacy: Evaluation with a Respiratory Bench Model

Patientengeräte in einer Gesundheitseinrichtung

Mimicking a flow-limited human upper airway using a collapsible tube: relationships between flow patterns and pressures in a respiratory model

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