Aorto-septal angle in Boxer dogs with subaortic stenosis: An echocardiographic study

Quintavalla, Cecilia; Guazzetti, Stefano; Mavropoulou, Antonia; Bussadori, Claudio

doi:10.1016/j.tvjl.2009.06.027

Cited by 15 publications

(20 citation statements)

References 18 publications

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“…In Boxers, AS seems to have a genetic background too; however, the causal locus (loci) has not been identified yet. The higher risk for AS in Boxers might be associated with some breed-specific conformational traits, like small aortic annulus and steep aortoseptal angle [69]. The incomplete penetrance of modifier genes together with autosomal dominant mode of inheritance may be the expected genetic base for AS in Boxers [32].…”

Section: Evidence For Genetic Backgroundmentioning

confidence: 99%

Aortic Stenosis in Dogs and Cats: Past, Present and Future

Petrič¹,

Perovič²,

Švara³

et al. 2019

Aortic Stenosis - Current Perspectives

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Aortic stenosis is one of the three most common congenital heart defects in dogs and less frequent in cats. Most dogs or cats have subvalvular type of stenosis; valvular or supravalvular types are less frequent. Heart failure is seldom a consequence of aortic stenosis; most dogs with heart failure have a concurrent disease. The most common accompanying diagnosis is pulmonic stenosis, especially in the Boxer breed. Screening programs seem to have efficiently lowered the incidence of aortic stenosis in dogs. Genetic evidence for aortic stenosis has been shown in Golden Retriever, Newfoundland and Dogue de Bordeaux; however, the genetic background of aortic stenosis at molecular level remains unclear.

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Section: Evidence For Genetic Backgroundmentioning

confidence: 99%

Aortic Stenosis in Dogs and Cats: Past, Present and Future

Petrič¹,

Perovič²,

Švara³

et al. 2019

Aortic Stenosis - Current Perspectives

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show abstract

“…24,55,92,104,106,128,201,283,365,370,[383][384][385][386][387][388][389][390][391][392] Typical SAS is characterized by a subvalvular ridge or tunnel that develops after birth; this is very evident on TEE examinations. 389,392 Flow and pressure abnormalities in AS can be defined by the continuity equation and the Bernoulli relationship, which were presented earlier in this chapter. 389,392 Flow and pressure abnormalities in AS can be defined by the continuity equation and the Bernoulli relationship, which were presented earlier in this chapter.…”

Section: Aortic Stenosismentioning

confidence: 99%

Echocardiography

Bonagura¹,

Fuentes²

2015

Small Animal Diagnostic Ultrasound

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“…Recently, a study conducted on Boxers demonstrated the influence of the angle between the aorta and interventricular septum on the growth of anomalous endocardial tissue [14]. The shear stress is increased when the angle is steeper (<140 degrees), causing endocardial proliferation [14], thus predisposing the Boxer to the development and progression of SAS ( Figure 19-1).…”

Section: Anatomopathologymentioning

confidence: 99%

“…The shear stress is increased when the angle is steeper (<140 degrees), causing endocardial proliferation [14], thus predisposing the Boxer to the development and progression of SAS ( Figure 19-1).…”

Section: Anatomopathologymentioning

confidence: 99%