Aortic valve replacement in middle-aged patients: Is the increased use of bioprostheses justified?

Glaser, Natalie; Sartipy, Ulrik

doi:10.1586/14779072.2016.1143361

Cited by 1 publication

(1 citation statement)

References 12 publications

(19 reference statements)

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“…Generally, the use of biological valves has increased [9,16], as also seen in our study. In our study population, however, the mean age of patients undergoing mechanical and biologic valve procedures stayed constant.…”

Section: Discussionsupporting

confidence: 84%

Population trends in aortic valve surgery in Finland between 2001 and 2016

Myllykangas

Gunn

Pietilä

et al. 2019

Scandinavian Cardiovascular Journal

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Objectives: To investigate nationwide changes in procedure rates, patient selection, and prognosis after all surgical aortic valve replacements.Design: Patients undergoing primary isolated surgical aortic valve replacement between 2001 and 2016 were identified from three nationwide registers with compulsory reporting to examine trends in aortic valve surgery over four four-year time periods.Results: A total of 12 139 isolated surgical aortic valve replacement procedures (mean age 61.9  11.8 years, 39.1% women) were performed between 2001 and 2016. The total number of biological valves increased fromThere was an increasing trend in use of biologic valves compared to mechanical valves 1001 (42.9%) to 2526 (75.5%) from 2001-2004 to 2013-2016 (p<0.001). During the first and last time periodsstudy period the comorbidity burden increased; the share of patients with hypertension increased from 37.5% to 46.9% (p<0.001), diabetes from 14% to 16.5% (p=0.01) and previous stroke from 5.2% to 7.2% (p=0.01) increased. The proportion of women undergoing surgery decreased from 40% to 36.1% from 2001-2004 to 2013-2016 respectively (p=0.01). OverallDuring the study period the 28-day mortality was 3.5 %. In patients with biologic valve the multivariable adjusted risk of shortterm mortality decreased steadily in every four-

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Section: Discussionsupporting

confidence: 84%