Aortic Valve Disease

Tamburino, Corrado

doi:10.1007/978-88-470-1424-4_3

Cited by 1 publication

(2 citation statements)

References 92 publications

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“…This occurs in 1-2% of the population and is more prevalent in males. 32 Certain characteristics define a BAV, including leaflets of different sizes or a central raphe between the largest leaflet and a smooth leaflet margin, even when diseased. 33 Differences in leaflet size occur in 92% of BAV cases and are most prevalent (86%) between the right and left coronary leaflets.…”

Section: Valvular Diseasesmentioning

confidence: 99%

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The aortic valve: structure, complications and implications for transcatheter aortic valve replacement

2014

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The aortic valve operates in a complex haemodynamic environment, opening and closing over 100,000 times a day. When complications arise, such as aortic stenosis, prognosis can be very poor, leading to death within the first few years. Surgical valve replacement is currently the standard treatment for aortic stenosis. A thorough understanding of the anatomy and function of the native valve is imperative when developing a prosthetic replacement that can withstand the complex demands of the heart. This review focuses on the anatomy, structure and disease of the aortic valve and the implications for a transcatheter aortic valve replacement (TAVR). Current complications with TAVR, such as major vascular bleeding, conduction disturbances and patient-prosthesis mismatch (PPM), can be overcome by reducing the delivery profile and through the use of more accurate imaging technologies to work towards a fully functional and durable prosthesis.

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Section: Valvular Diseasesmentioning

confidence: 99%

“…47,48 In chronic cases, the left ventricular volume leads to ventricular hypertrophy and recruitment of sarcomeres to accommodate the increase in volume. 32 Therefore, a normal physiological stroke volume and ventricular diastolic pressure are maintained. Patients with chronic aortic regurgitation may be asymptomatic for decades.…”

Section: Valvular Diseasesmentioning

confidence: 99%