Aortic stiffness in degenerative aortic stenosis

Abstract

Aortic stenosis (AS) is one of the most common cardiovascular diseases. The prevalence of AS and vascular stiffness are significantly associated with age. Elevated arterial stiffness is an independent risk factor for cardiovascular events. The pathogenetic and clinical relationship of degenerative AS and aortic stiffness is poorly known. This review reflects the current understanding of the relationship between degenerative AS and aortic stiffness. The existing evidence on the effects of surgical and endovascular correction of the defect on aortic stiffness is described. The potential predictors of AS prognosis and outcomes of valve replacement are discussed. Unresolved issues and directions for further research are clarified.