Aortic regurgitation in rheumatoid arthritis necessitating aortic valve replacement

Levine, Arlene B.

doi:10.1016/s1010-7940(98)00294-2

Cited by 18 publications

(13 citation statements)

References 13 publications

(11 reference statements)

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“…In an autopsy study of 188 patients with rheumatoid arthritis, a 5.3% prevalence of aortitis and 1.6% prevalence of aneurysm formation were reported (32). The aortic valve and annulus may also be affected with granulomatous or nongranulomatous inflammation, leaflet thickening, and secondary regurgitation (33).…”

Section: Other Rheumatic Diseases Associated With Aortitismentioning

confidence: 99%

Aortitis: Imaging Spectrum of the Infectious and Inflammatory Conditions of the Aorta

et al. 2011

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Aortitis is a general term that refers to a broad category of infectious or noninfectious conditions in which there is abnormal inflammation of the aortic wall. These inflammatory conditions have different clinical and morphologic features and variable prognoses. The clinical manifestations are usually vague and nonspecific and may include pain, fever, vascular insufficiency, and elevated levels of acute phase reactants, as well as other systemic manifestations. As a result, aortitis is often overlooked during the initial work-up of patients with constitutional symptoms and systemic disorders. A multimodality imaging approach is often required for assessment of both the aortic wall and aortic lumen, as well as for surveillance of disease activity and treatment planning. Noninvasive cross-sectional imaging modalities such as magnetic resonance (MR) imaging, MR angiography, and computed tomographic angiography play a critical role in initial evaluation and further assessment of aortitis. Radiologists should be familiar with the clinical features and imaging findings of the different types of aortitis.

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Section: Other Rheumatic Diseases Associated With Aortitismentioning

confidence: 99%

Aortitis: Imaging Spectrum of the Infectious and Inflammatory Conditions of the Aorta

et al. 2011

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“…Although all four major valves can be affected by rheumatoid nodules, mitral valve involvement occurs more frequently than aortic or tricuspid [9]. The literature suggests that aortic regurgitation may be more likely to produce functional impairment than mitral regurgitation [10], and some cases of AR progress to abrupt decompensation requiring emergency valve replacement [11] [12].…”

Section: Discussionmentioning

confidence: 99%

Rheumatoid Nodule Causing Perforation of Anterior Mitral Leaflet and Severe Mitral Regurgitation: A Rare Case Report

Koneru¹,

Cholankeril²,

Shah³

et al. 2014

WJCD

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Rheumatoid arthritis (RA) is a systemic disorder that is chronic in nature and difficult to treat. RA presents in many variants. Here we present an interesting case only seldom described before. Our patient presented to emergency room with acute shortness of breath and was seen to have acute pulmonary edema. Patient later had urgent echocardiography which revealed severe mitral regurgitation from ruptured anterior leaflet. Patient was taken for heart valve replacement and was found to have RA nodule on ruptured leaflet. There are cases involving aortic valve but to our knowledge there are no reports of RA nodule on mitral leaflet.

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“…The aortic valve and annulus may also be affected by granulomatous or nongranulomatous inflammation, leaflet thickening and secondary regurgitation [78]. Involvement of the coronary ostia, if present, may lead to myocardial ischaemia [15].…”

Section: Noninfectious Aortitismentioning

confidence: 99%

Insights into imaging of aortitis

2012

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BackgroundAortitis is a subtype of the more general term “vasculitis”, an inflammatory condition of infectious or noninfectious origin involving the vessel wall. The term “vasculitis” refers to a broad spectrum of diseases with different aetiologies, pathophysiologies, clinical presentations and prognoses. The clinical manifestations are nonspecific, as are the laboratory findings such as pain, fever, weight loss, vascular insufficiency and elevated levels of acute phase reactants, as well as other systemic manifestations, and sometimes may mimic other entities. Thus, if not suspected as part of the initial differential diagnosis, aortitis can be overlooked during the workup of patients with constitutional symptoms and systemic disorders. Methods: Imaging is rarely used for the primary diagnosis, but imaging findings, although nonspecific, can help in the assessment of these patients and is often required for making the final diagnosis. Imaging can be critical in the initiation of appropriate management and therapy. Results: Noninvasive cross-sectional imaging modalities such as contrast-enhanced CT, magnetic resonance (MR) imaging, nuclear medicine and in particular positron emission tomography (PET) are the leading modalities in modern diagnostic imaging of aortitis for both the initial diagnosis and follow-up. Conclusion: This review focusses on the most common manifestations of aortitis with which radiologists should be familiar.Teaching Points• Aortitis is an inflammatory condition of infectious/noninfectious origin involving the vessel wall.• Imaging findings can help in the assessment of aortitis and are often crucial for the final diagnosis.• Contrast-enhanced CT, MRI and PET-CT are used for both the initial diagnosis and follow-up of aortitis.

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Aortic regurgitation in rheumatoid arthritis necessitating aortic valve replacement

Cited by 18 publications

References 13 publications

Aortitis: Imaging Spectrum of the Infectious and Inflammatory Conditions of the Aorta

Aortitis: Imaging Spectrum of the Infectious and Inflammatory Conditions of the Aorta

Rheumatoid Nodule Causing Perforation of Anterior Mitral Leaflet and Severe Mitral Regurgitation: A Rare Case Report

Insights into imaging of aortitis

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