“…However, compared with Bentall interventions, valve-sparing root replacements are less appealing for the elderly as a result of frequent aortic leaflet disorders, increased technical complexity, longer operational duration, and not excludable greater durability of biological valve prostheses [43] (Fig 7). Therefore, the present systematic review was conducted, with emphasis on early-and long-term outcomes, to evaluate the existing evidence for aortic root replacement with a biological valved conduit.…”