Aortic involvement in giant cell arteritis: Current data

Coronary Artery Disease and Systemic Vasculitis: Case Report and Review

“…However, despite major www.intechopen.com immunosuppressive care, systemic vasculitis may lead to potential fatal complications and death, through diffuse vessel fibrinoid necrosis and interstitial hemorrhages, attaching multiple organs. (Andersson, 2000;Bossert, et al 2011;Eberhardt & Dhadly, 2007;Freddo et al, 1999;Lin, et al, 2007;Osman & McCreery, 2000;Wegner & Schneider, 1996).…”

“…(Bossert et al, 2011;Eberhardt & Dhadly, 2007;Kimura et al, 2011;Lin, et al, 2007). Giant cell-related early myocardial infarction, often with fatal outcome, is more commonly reported than previously appreciated.…”

“…(Andersson, 2000;Bossert et al, 2011;Eberhardt & Dhadly, 2007;Freddo et al, 1999;Lin et al, 2007;Wegner & Schneider, 1996).…”

“…(Bossert et al, 2011;Kimura et al, 2011;Lin et al, 2007;Mavrogeni et al, 2009). Directional coronary atherectomy can also be an alternative diagnostic method for coronary giant arteritis.…”

Large-Vessel Giant Cell Arteritis Presenting as Back Pain with Vertebral Body Infarction in a 73-year-old Caucasian Woman

“…Although classically affecting the arteries arising from the aortic arch, in particular the temporal and ophthalmologic arteries, in our case there was no known cranial involvement, but severe vasculitis causing vertebral bone infarction in the thoracic spine. While aortitis may present clinically in 3% to 18% of temporal arteritis patients, a recent study showed that aortic involvement may be present in over 50% of cases when imaging with positron emission tomography and MRI was used 7 . While complications such as aneurysms, vascular dissection, strokes, myocardial infarction, and even mesenteric ischemia have been described, GCA causing vertebral body infarction is a previously unreported complication 8 .…”