“…Although there are similarities, there are, at times, clinical, laboratory, and biochemical differences, particularly regarding prevalence, etiology, possible mechanisms of thrombosis, clinical presentations, diagnosis, and at times, management [4,5]. The ACLA-thrombosis antiphospholipid syndrome is much more common than the LA-thrombosis antiphospholipid syndrome, the ratio being approximately 5 to 1 [3,6,7]. All of these syndromes may be associated with (1) arterial and venous thrombosis, (2) recurrent miscarriage, and (3) thrombocytopenia, in descending order of prevalence; however, the anticardiolipin syndrome is associated more commonly with both arterial and venous thrombosis, including typical deep vein thrombosis and pulmonary embolus, premature coronary artery disease, premature cerebrovascular disease (including TIAs, small-stroke syndrome, and cerebrovascular thrombotic stroke), and retinal arterial and venous occlusive disease.…”