Aortic Arch Reconstruction: Safety of Moderate Hypothermia and Antegrade Cerebral Perfusion During Systemic Circulatory Arrest

Cook, R.C.M.; Gao, Min; Macnab, Andrew; Fedoruk, Lynn M.; Day, Nancy L.; Janusz, Michael T.

doi:10.1111/j.1540-8191.2006.00191.x

Cited by 47 publications

(35 citation statements)

References 24 publications

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“…Cook and associates [17] demonstrated a comparable incidence of neurologic injury in groups of patients undergoing HCA and ASCP at moderate hypothermia (!22 8C) and deep hypothermia (<22 8C). Besides, lower rates of major neurologic injury and delirium were observed in the group of moderate hypothermia.…”

Section: Discussionmentioning

confidence: 96%

Antegrade selective cerebral perfusion in thoracic aorta surgery: safety of moderate hypothermia

Pacini

Leone

Marco

et al. 2007

European Journal of Cardio-Thoracic Surgery

126

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In our experience, ASCP was a safe technique for thoracic aorta surgery allowing complex aortic repairs to be performed with good results in terms of hospital mortality and neurologic outcomes. The fact that there was no difference between the two groups suggests that moderate systemic hypothermia (26 degrees C) appears to be a safe and sufficient tool for brain protection. Moreover, the well known hypothermia-related side effects may be avoided.

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Section: Discussionmentioning

confidence: 96%

Antegrade selective cerebral perfusion in thoracic aorta surgery: safety of moderate hypothermia

Pacini

Leone

Marco

et al. 2007

European Journal of Cardio-Thoracic Surgery

126

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“…When repairing an AAD, brain preservation is still one of the major challenges during surgery, and failure to do so is the best predictor of hospital mortality [57]. Cook et al [58] showed that a systemic temperature of below 22 C may not be necessary and may be associated with a higher incidence of neurological injury when SACP is used during deep hypothermic arrest. Salazar et al [59] supported the conclusion that systemic circulatory arrest with SACP at moderate hypothermia can be safely performed.…”

Section: Surgical Treatmentmentioning

confidence: 99%

Acute aortic dissection: An update

Ayala

Chen

2012

The Kaohsiung J of Med Scie

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The aorta, which has a complex intrinsic biology and sophisticated mechanical properties for conducting the blood ejected from the left ventricle to the rest of the systemic arterial bed, is the largest and strongest artery in the body. It carries roughly 200 million liters of blood in an average lifetime. Any process that undermines the architecture threatens the structure, stability, and functionality of the aorta. In this regard, acute aortic dissection (AAD) requires special attention because it is the most catastrophic acute illness of the aorta; it has high morbidity and mortality because of potentially fatal complications. AAD has, therefore, become an important topic of recent research, and knowledge about this disease has improved during the past few years. Up-to-date knowledge about the natural history, epidemiology, presentation, physiopathology, evolution, management, follow-up, and long-term outcomes of AAD are summarized in this review.

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“…Moreover, Cook and colleagues reported that systemic temperatures below 22°C may not be necessary and could even be associated with a higher incidence of neurologic injury when ACP is used during DHA. 6 Greeley and colleagues reported that patients cooled to 28°C had a predicted brain ischemic tolerance of 11-19 min. 7 Our results suggest that moderate hypothermic arrest at 28°C without any adjunctive Fig.…”

Section: Discussionmentioning

confidence: 99%

Less invasive quick replacement of the proximal arch with aggressive rapid rewarming for type A acute aortic dissection

et al. 2009

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We describe a newly modified technique, which we term "less invasive quick replacement" (LIQR) for type A acute aortic dissection (AAD). After cooling to a rectal temperature of 28 degrees C without any cerebral perfusion, circulating blood in the cardiopulmonary bypass (CPB) circuit was warmed up to 40 degrees C during open distal anastomosis. As soon as the distal anastomosis was completed, rapid rewarming was initiated by perfusing blood at 40 degrees C. The average CPB and total operative times were 71.8 +/- 9.6 and 130.6 +/- 7.7 min, respectively. The shortest operative time was 101 min from skin incision to skin closure. All patients were weaned off the ventilator within 12 h of surgery. The postoperative hospital stay was 9.3 +/- 1.2 days. There was no incidence of cerebral damage or hospital mortality. Our initial results showed LIQR to be safe and effective.

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Aortic Arch Reconstruction: Safety of Moderate Hypothermia and Antegrade Cerebral Perfusion During Systemic Circulatory Arrest

Cited by 47 publications

References 24 publications

Antegrade selective cerebral perfusion in thoracic aorta surgery: safety of moderate hypothermia

Antegrade selective cerebral perfusion in thoracic aorta surgery: safety of moderate hypothermia

Acute aortic dissection: An update

Less invasive quick replacement of the proximal arch with aggressive rapid rewarming for type A acute aortic dissection

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