Abstract:IntroductionInflammatory bowel disease-associated colorectal cancers (IBD-CRCs) occur infrequently but are associated with a higher mortality than sporadic CRCs. The poorly defined genetic and molecular pathogenesis of IBD-CRCs limits our ability to develop effective prevention, detection and treatment strategies. Since molecular changes identified at the time of surgery are most likely to represent informative biomarkers we elected to study primary IBD-CRC.Method6The study was approved by the Lothian NHS Rese… Show more
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