Anxiolytic and antidepressant-like effect of the ethanolic extract of Cassia tora seed in Swiss mice

Shrivastava, Amit Kumar; Shrestha, Laxmi; Gurung, Shanti; Joshi, Bishal

doi:10.5455/jcmr.2020.11.01.01

Cited by 5 publications

(2 citation statements)

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“…The total time spent in open and closed arms was recorded for 6 min,. The average time spent per entry in the open arm of EPM was used to measure anxiety level at 0, 2, 4, and 6th days of experiment [ 37 , 38 ].…”

Section: Methodsmentioning

confidence: 99%

Effect of aqueous extract of barley and wheat grass in stress induced depression in Swiss mice

Shrivastava

Magar

Shrestha

2022

Journal of Ayurveda and Integrative Medicine

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Section: Methodsmentioning

confidence: 99%

Effect of aqueous extract of barley and wheat grass in stress induced depression in Swiss mice

Shrivastava

Magar

Shrestha

2022

Journal of Ayurveda and Integrative Medicine

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“…The mice were considered immobile when they were ceased struggling and remained floating motionless in water, making only the movement to keep their head above water. 13 Tail Suspension Test Tail suspension test is also performed for screening the antidepressant like activity in mice, was done by Steru., et.al. Firstly prior to the laboratory test, animals were brought in the lab to adapt the lab condition for 1-2 hr.…”

Section: Forced Swimming Testmentioning

confidence: 99%

Anti-depressant Activity of the Seeds of Zanthoxylum armatum on Swiss Albino Mice

Yadav

Poudel

Mehta

et al. 2022

Nep. J. Health Sci.

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Introduction: Depression disorder has significant potential morbidity and mortality, contributing to suicide, incidence and adverse outcomes of medical illness, disruption in interpersonal relationships, substance abuse, and lost work time. Objectives: The present study was designed to study the anti-depressant activity of the seeds extract of Zanthoxylum armatum using a forced swim test and tail suspension test on Swiss albino mice. The anti-depressant activity of the seeds of Zanthoxylum armatum was assessed using Chronic Unpredictable Mild-Stress (CUMS) induced depression in mice. Methods: The animals were treated with the methanolic extract of seeds of Zanthoxylum armatum orally at two doses of 100, 200mg/kg body weight for eight days after CUMS induced depression in mice. The results demonstrate that Methanolic extract of seeds of Zanthoxylum armatum has got anti-depressant potential. Results: The study showed that the extract of Zanthoxylum armatum had significant antidepressant activity. Microsoft Excel was used to calculate the mean ± SEM and one-way ANOVA followed by a turkey multiple comparison test was used to analyze the results. The seed extract presented significant antidepressant activity in mice (p<0.05). Conclusions: This study was conducted to explore the antidepressant activity of seeds extracts of plant Zanthoxylum armatum in CUMS induced mice.

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Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications

et al. 2022

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Background : The worldwide corona virus disease outbreak, generally known as COVID-19 pandemic outbreak resulted in a major health crisis globally. The morbidity and transmission modality of COVID-19 appear more severe and uncontrollable. The respiratory failure and following cardiovascular complications are the main pathophysiology of this deadly disease. Several therapeutic strategies are put forward for the development of safe and effective treatment against SARS-CoV-2 virus from the pharmacological view point but till date there are no specific treatment regimen developed for this viral infection. Purpose : The present review emphasizes the role of herbs and herbs-derived secondary metabolites in inhibiting SARS-CoV-2 virus and also for the management of post-COVID-19 related complications. This approach will foster and ensure the safeguards of using medicinal plant resources to support the healthcare system. Plant-derived phytochemicals have already been reported to prevent the viral infection and to overcome the post-COVID complications like parkinsonism, kidney and heart failure, liver and lungs injury and mental problems. In this review, we explored mechanistic approaches of herbal medicines and their phytocomponenets as antiviral and post-COVID complications by modulating the immunological and inflammatory states. Study design : Studies related to diagnosis and treatment guidelines issued for COVID-19 by different traditional system of medicine were included. The information was gathered from pharmacological or non-pharmacological interventions approaches. The gathered information sorted based on therapeutic application of herbs and their components against SARSCoV-2 and COVID-19 related complications. Methods : A systemic search of published literature was conducted from 2003 to 2021 using different literature database like Google Scholar, PubMed, Science Direct, Scopus and Web of Science to emphasize relevant articles on medicinal plants against SARS-CoV-2 viral infection and Post-COVID related complications. Results : Collected published literature from 2003 onwards yielded with total 625 articles, from more than 18 countries. Among these 625 articles, more than 95 medicinal plants and 25 active phytomolecules belong to 48 plant families. Reports on the therapeutic activity of the medicinal plants belong to the Lamiaceae family (11 reports), which was found to be maximum reported from 4 different countries including India, China, Australia, and Morocco. Other reports on the medicinal plant of Asteraceae (7 reports), Fabaceae (8 reports), Piperaceae (3 reports), Zingiberaceae (3 reports), Ranunculaceae (3 reports), Meliaceae (4 reports) were found, which can be explored for the development of safe and efficacious products targeting COVID-19. Conclusion : K...

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Anxiolytic and antidepressant-like effect of the ethanolic extract of Cassia tora seed in Swiss mice

Cited by 5 publications

References 0 publications

Effect of aqueous extract of barley and wheat grass in stress induced depression in Swiss mice

Effect of aqueous extract of barley and wheat grass in stress induced depression in Swiss mice

Anti-depressant Activity of the Seeds of Zanthoxylum armatum on Swiss Albino Mice

Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications

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