Anxiolytic activity of Panax ginseng roots: an experimental study

Bhattacharya, Sujit; Mitra, Sumit

doi:10.1016/0378-8741(91)90193-h

Cited by 110 publications

(60 citation statements)

References 14 publications

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“…Confirming previous results (Bhattacharya, Mitra, 1991), the i.p. administration of diazepam (1 mg/kg) resulted in anxiolytic-like effect, characterized by an increase in the percentage of exploration in the open arms of the plus maze (Fig.…”

Section: Discusionsupporting

confidence: 81%

Sedative and anxiolytic effects of methanolic extract from the leaves of Passiflora actinia

Santos

Kurtz

Müller

et al. 2006

Braz. arch. biol. technol.

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Section: Discusionsupporting

confidence: 81%

Sedative and anxiolytic effects of methanolic extract from the leaves of Passiflora actinia

Santos

Kurtz

Müller

et al. 2006

Braz. arch. biol. technol.

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“…35) Ginseng Radix is also known to be useful for treatment of stress-related disorders like peptic ulcer, depression, and anxiety disorder. 36,37) Central administration of Ginseng saponin affected NPY mRNA expression in the hypothalamic paraventiricular nucleus. 38) Thus Pinelliae Tuber, Zingiberis Rhizoma, and Ginseng Radix, or their combinations, might affect plasma NPY levels.…”

Section: Fig 2 Elution Profiles Of Plasma Extracts By Hplc On a C 1mentioning

confidence: 99%

Effects of Some Kampo Medicines on Plasma Levels of Neuropeptide Y under Venipuncture Stress

Sato

Katagiri

Takeyama

2005

Biological & Pharmaceutical Bulletin

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Some traditional Chinese herbal (Kampo) medicines have recently been evaluated for their clinical usefulness in stress and depression. These medicines have modulatory effects on the hypothalamic-pituitary-adrenal axis and sympathetic nervous system (SNS). We examined the effects of Rikkunshi-to, Hange-shashin-to, Hangekoboku-to, and Ninjin-to on plasma levels of neuropeptide Y (NPY), which is the representative neurotransmitter of the SNS, under venipuncture stress. Rikkunshi-to and Hange-shashin-to suppressed increases in plasma NPY-immunoreactive substance levels compared with the response to a placebo. In this study, Rikkunshi-to and Hange-shashin-to altered plasma levels of NPY under venipuncture stress. These effects might be benefical in stress-related diseases and our results suggest that these medicines have clinical pharmacologic activity.

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“…(Key words : laying hen, heat stress, immune, red ginseng marc) † To whom correspondence should be addressed : john8604@korea.kr (Kwak et al, 2003;Bhattachary and Mirata, 1991). 홍삼 진액를 추출한 후에는 부산물이 발생하는 데 홍삼 부산물(홍삼박)의 경우, 사포닌과 함께상당한양의 다당체가 용출되지 않고 함유되어 있다 (Chang et al, 2007).…”

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“…In conclusion, although ineffective as inhibiter in thermal stress, dietary supplementation of Red Ginseng marc improved SOD like activity and immune system by regulating immunoglobulin content in laying hens. These findings have laid the foundation for future studies of immunomodulation in laying hens fed Red Ginseng Marc and of evaluation of heat stress inhibitor.(Key words : laying hen, heat stress, immune, red ginseng marc) † To whom correspondence should be addressed : john8604@korea.kr (Kwak et al, 2003;Bhattachary and Mirata, 1991). 홍삼 진액를 추출한 후에는 부산물이 발생하는 데 홍삼 부산물(홍삼박)의 경우, 사포닌과 함께상당한양의 다당체가 용출되지 않고 함유되어 있다 (Chang et al, 2007).…”

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confidence: 99%

Effect of Feeding Red Ginseng Marc on Vital Reaction in Laying Hens under Stress Task

Hong¹,

Bong²,

Park³

et al. 2012

Korean Journal of Poultry Science

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This study was conducted to determine the possible use of Red Ginseng marc as stress inhibiter in thermal stress (temperature humidity index 86) and lipopolysaccharide (LPS) -exposed laying hens by investigating their effects on laying performance, blood biochemical parameters, immunoglobulin concentration and serum superoxide dismutase (SOD) like ability. A total of forty-five 52-wk-old laying hens (ISA Brown) were divided into 3 treatment groups with 5 replicates of 3 birds in each group. NC (negative control, no immune substances), PC (positive control, β-glucan 25 ppm) and RGM (Red Ginseng Marc 3%) were added in feed with respective substance. Egg production in RGM was significantly increased in comparison with NC groups for 8 weeks (P<0.05). On blood biochemical parameters, effects of ambient temperature is definite by showing significant difference in aspartate aminotransferase and others (P<0.05), but RGM both before and after thermal stimulation have no significant difference in comparison with other groups. And for 3 weeks after thermal stimulation, laying performance was also not significantly different among treatments. Immunoglobulin M content and SOD like activities after challenge with LPS were higher in the RGM and PC than NC (P<0.05). In conclusion, although ineffective as inhibiter in thermal stress, dietary supplementation of Red Ginseng marc improved SOD like activity and immune system by regulating immunoglobulin content in laying hens. These findings have laid the foundation for future studies of immunomodulation in laying hens fed Red Ginseng Marc and of evaluation of heat stress inhibitor.(Key words : laying hen, heat stress, immune, red ginseng marc) † To whom correspondence should be addressed : john8604@korea.kr (Kwak et al., 2003;Bhattachary and Mirata, 1991). 홍삼 진액를 추출한 후에는 부산물이 발생하는 데 홍삼 부산물(홍삼박)의 경우, 사포닌과 함께상당한양의 다당체가 용출되지 않고 함유되어 있다 (Chang et al., 2007). 이러한 홍삼박의 산성 다당체 역시 항암 및 면

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Anxiolytic activity of Panax ginseng roots: an experimental study

Cited by 110 publications

References 14 publications

Sedative and anxiolytic effects of methanolic extract from the leaves of Passiflora actinia

Sedative and anxiolytic effects of methanolic extract from the leaves of Passiflora actinia

Effects of Some Kampo Medicines on Plasma Levels of Neuropeptide Y under Venipuncture Stress

Effect of Feeding Red Ginseng Marc on Vital Reaction in Laying Hens under Stress Task

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