Anxiety disorders are associated with early onset of heroin use and rapid transition to dependence in methadone maintained patients

Karsinti, Emily; Fortias, Maeva; Dupuy, Gaël; Ksouda, Kamilia; Laqueille, Xavier; Simonpoli, Anne-Marie; Touzeau, Didier; Avril, Elisabeth; Orizet, Cyrille; Belforte, Beatriz; Coeuru, Philippe; Poloméni, Pierre; Icick, Romain; Jarroir, M.; Bloch, Vanessa; Scott, Jan; Lépine, Jean‐Pierre; Bellivier, Frank; Vorspan, Florence

doi:10.1016/j.psychres.2016.04.064

Cited by 5 publications

(2 citation statements)

References 16 publications

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“…His anticipatory anxiety led to a maladaptive focus on negative cognitions. 16 17 However, encouraged by the strong family support, societal functionality and lack of any major active mental illnesses, we helped the patient switch from methadone to buprenorphine by prescribing TCM, with a strong focus on relieving his opioid withdrawal symptoms and controlling his anxiety symptoms.…”

Section: Discussionmentioning

confidence: 99%

Traditional Chinese medicine-facilitated treatments may relieve anxiety symptoms during drug switching from methadone to buprenorphine/naloxone for treating opioid dependence

Wei

Yeh

et al. 2017

BMJ Case Reports

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This study investigated a 51-year-old married man with a history of heroin dependence who underwent methadone maintenance treatment for 7 years. He received traditional Chinese medicine (TCM)-facilitated treatments and switched from methadone to buprenorphine/naloxone. Strong anxiety symptoms were observed during the initial stage; therefore, we prescribed a combination of Chaihu-Shugan-San, Zhi Bai Di Huang and Chin-Gin-Kuan-Ming decoction as the major herbal synergic regimen to relieve the symptoms of opioid withdrawal, anxiety and insomnia. During the treatment course, no precipitating withdrawal syndromes were noted, and the subject was gradually relieved of his anxiety symptoms through continual TCM treatments. In conclusion, TCM is effective in facilitating the switch from methadone to buprenorphine/naloxone and relieving anxiety symptoms. Therefore, focus on TCM-facilitated treatments for heroin dependence should be increased.

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Section: Discussionmentioning

confidence: 99%

Traditional Chinese medicine-facilitated treatments may relieve anxiety symptoms during drug switching from methadone to buprenorphine/naloxone for treating opioid dependence

Wei

Yeh

et al. 2017

BMJ Case Reports

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“…They could lead to a higher risk of overdose (38%) and imprisonment and lower chance to ever get married. The study also mentioned they have mood (61%) and anxiety (53%), mood disorders and suicidal attempted (31%) (Karsinti et al, 2016).…”

Section: Heroin Users Related Risk Behaviorsmentioning

confidence: 91%

Patterns of Heroin Use and Risk Behaviors Among Prisoners in Colombo,sri Lanka

Dissanayake

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Heroin is a highly addictive drug which affect a number of problems for users as well as society. However, there were no any recent data regarding heroin users among prisoner in Sri Lanka. This study aimed to identify the patterns of heroin use, risk behaviors and level of addiction among male prisoners in Sri Lanka. A face to face interview questionnaire was administrated purposively sampling among 334 heroin users aged 18 years and above. The average of age was 37.8 ? 6.1 while average age of heroin first used was 30.8 ? 4.2. Drug use was largely introduced from friends (86%) and peer pressure was the main reason to use heroin (93%). Smoking is the main route of administration (Almost 98%). Nearly 96% reported that they used every day. Only 5% reported drug overdose experience. Among them nearly 53% had two times of overdosing. Tobacco smoking and alcohol use were more prominent (62.6%, 76.3% respectively). There was a high prevalence (81%) of risk behavior with multiple partners. Tattoo making experienced was 37%. The majority (93%) had ever been arrested. Drug trafficking, heroin using and crimes were prominent reasons (55%, 9.4%, 8.7% respectively). Most heroin users were severely addictive (98%). It is essential for policy makers to provide prevention program and harm reduction for heroin use., overdose and risk behaviors among this group prior going out from the prison and living in the society.

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