Anxiety, depression and swallowing disorders in patients with Parkinson's disease

Manor, Yosef; Balas, Meirav; Giladi, Nir; Mootanah, Rajshree; Cohen, Jacob T.

doi:10.1016/j.parkreldis.2008.11.005

Cited by 52 publications

(38 citation statements)

References 19 publications

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“…In agreement with other studies (Miller et al 2006, Han et al 2011, Plowman-Prine et al 2009, Manor et al 2009) we found a weak-moderate association of reported swallowing problems with depression. The association requires further investigation.…”

Section: Discussionsupporting

confidence: 93%

Perceived changes to swallowing in people with Parkinson's disease

Noble

Jones

Miller

2015

International Journal of Therapy and Rehabilitation

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Section: Discussionsupporting

confidence: 93%

Perceived changes to swallowing in people with Parkinson's disease

Noble

Jones

Miller

2015

International Journal of Therapy and Rehabilitation

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“…Because the MOCA survey is more time consuming than age determination, age was retained and MOCA excluded. Finally, nine factors described as possible dysphagia risk factors were included in the analysis, the scale and coding of which are given in brackets: age (years), gender (male = 0, female = 1), BMI (metric), affirmed subjective aspiration signs ("no" = 0, "yes" = 1), NMS‐Quest 3 ("no" = 0, "yes" = 1), MDS‐UPDRS III score (metric), BDI‐II score (metric), DBS (absent = 0, present = 1), and disease duration (years). The binary logistic regression analysis showed that affirmed subjective aspiration signs, gender, and higher age were significantly associated with the risk of critical aspiration (Table ).…”

Section: Resultsmentioning

confidence: 99%

Predictive clinical factors for penetration and aspiration in Parkinson's disease

Nienstedt

Bihler

Niessen

et al. 2018

Neurogastroenterology Motil

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Background Do the current swallow‐specific subquestions of neurological diagnostic tools reflect the objective swallowing function in Parkinson's disease (PD) patients or are clinical factors superior to predict critical aspiration? Methods In a cross‐sectional, observational study a total of 119 Parkinson outpatients were examined clinically and by flexible‐endoscopic evaluation of swallowing (FEES). Self‐reported dysphagia by subquestions of the MDS‐UPDRS and NMS questionnaire and history of subjective aspiration signs were collected. Key Results Nearly, all PD patients showed deglutition abnormalities in FEES (113/119) while only 12%‐27% of them reported swallowing problems in the swallow‐specific subquestions of neurological standard diagnostic tools (MDS‐UPDRS and NMS‐Quest), and the answers were heterogeneous and poorly reproducible. With a sensitivity of up to a maximum of 50%, self‐reported dysphagia is therefore no reliable tool for identifying dysphagia in PD. While most clinical parameters were linked to dysphagia to some extent, logistic regression analysis revealed high age (Odds Ratio (OR) 1.1 in years, 95% CI 1.03‐1.18, P < 0.01), gender (OR 0.3 for females, 95% CI 0.08‐0.97, P = 0.04), and affirmed subjective aspiration signs (OR 8.6, 95% CI 3.05‐26.52, P < 0.001) as the most significant predictors for critical dysphagia. Conclusions and Inferences Self‐perception of swallowing is no reliable tool for identifying dysphagia and questionnaires are insufficient for detecting previous aspiration. Consequent and specific asking for previous subjective aspiration signs is the single most important measure for identifying PD patients at risk for critical aspiration.

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“…They are associated with drooling and present health and social challenges to people with PD (PwPD) with increased susceptibility to chest infection, one of the commonest causes of death in PD (Kalf et al 2007, Fall et al 2003). Swallowing changes impact too on family members (Miller et al 2006a, Manor et al 2009).…”

Section: Introductionmentioning

confidence: 99%