Anxiety and impulsivity levels identify relevant subtypes in adolescents with at-risk behavior

Askénazy, Florence; Sorci, K.; Benoît, Michel; Lestideau, Karine; Myquel, M.; Lecrubier, Y.

doi:10.1016/s0165-0327(02)00455-x

Cited by 63 publications

(33 citation statements)

References 31 publications

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“…The odds that children and adolescents with conduct disorder also present with comorbid impulse control disorders during their lifetimes were found in the National Comorbidity Survey Replication to be over seven times greater than for those participants without conduct disorder (Nock et al 2006). This is consistent with evidence that impulsivity is highly predictive of conduct disorder in adolescents (Askenazy et al 2003;Vitacco and Rogers 2001).…”

Section: Introductionsupporting

confidence: 61%

Systematic review of pharmacotherapy of disruptive behavior disorders in children and adolescents

Ipser

Stein

2006

Psychopharmacology

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Section: Introductionsupporting

confidence: 61%

Systematic review of pharmacotherapy of disruptive behavior disorders in children and adolescents

Ipser

Stein

2006

Psychopharmacology

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“…Impaired inhibitory control contributes to substance misuse. Individuals who bear an impulsive personality trait or who demonstrate impulsive behaviors are more likely to engage in substance misuse (Acton, 2003;Askenazy et al, 2003;Butler and Montgomery, 2004;Cloninger, 1988;Dawe, 2004;Masse and Tremblay, 1997;Moeller, 2001;Tarter et al, 2003;Tarter et al, 2004). For instance, in a sample of more than one thousand adolescents, indicators of disinhibition assessed at age 11 predicted age of first drink at age 14 (McGue et al, 2001).…”

Section: Cognitive Inhibitory Controlmentioning

confidence: 99%

Inhibitory control and emotional stress regulation: Neuroimaging evidence for frontal–limbic dysfunction in psycho-stimulant addiction

Sinha

2008

Neuroscience & Biobehavioral Reviews

303

214

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This review focuses on neuroimaging studies that examined stress processing and regulation and cognitive inhibitory control in patients with psycho-stimulant addiction. We provide an overview of these studies, summarizing converging evidence and discrepancies as they occur in the literature. We also adopt an analytic perspective and dissect these psychological processes into their subcomponents, to identify the neural pathways specific to each component process and those that are more specifically involved in psycho-stimulant addiction. To this aim we refer frequently to studies conducted in healthy individuals. Despite the separate treatment of stress/affect regulation, stressrelated craving or compulsive drug seeking, and inhibitory control, neural underpinnings of these processes overlap significantly. In particular, the ventromedial prefrontal regions including the anterior cingulate cortex, amygdala and the striatum are implicated in psychostimulant dependence. Our overarching thesis is that prefrontal activity ensures intact emotional stress regulation and inhibitory control. Altered prefrontal activity along with heightened striatal responses to addicted drug and drug-related salient stimuli perpetuates habitual drug seeking. Further studies that examine the functional relationships of these neural systems will likely provide the key to understanding the mechanisms underlying compulsive drug use behaviors in psycho-stimulant dependence. Keywords fMRI; cognitive control; reward; motivation; affect; impulsivity; decision making; cocaine; methamphetamine The molecular and cellular neurobiology of drug addiction has recently been extensively reviewed in the literature (Di Chiara and Bassareo, 2007;Kalivas et al., 2005;Koob, 2006;Maldonado et al., 2006). Drawing heavily on rodent studies, previous reviews of the neuroscience of drug addiction have elaborated on the role of cortico-striatal pathways and extended amygdala circuitry in shaping habitual and compulsory drug use behaviors (Everitt et al., 2001;Everitt and Robbins, 2005;Everitt and Wolf, 2002;Koob, 2003;Koob, 2006; Address correspondence to: Dr. Chiang-shan Ray Li, Assistant Professor, Connecticut Mental Health Center, S103, Department of Psychiatry, Yale University School of Medicine, 34 Park Street New Haven, CT 06519,. Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. NIH Public Access Author ManuscriptNeurosci Biobehav Rev. Author manuscript; available in PMC 2009 January 1. Published in final edited form as:Neurosci Biobehav Rev. 2008 ; 32(3): 581-597. NIH-PA Author ManuscriptNIH-PA Author Manusc...

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“…Of the 65 papers included here, overwhelmingly most (n = 53) 28,30-81 were concerned with the identification and/or the assessment and/or the management of suicide risk, followed by the risks to self which are associated with alcohol and drug abuse (n = 7). [82][83][84][85][86][87][88] Smaller numbers of included papers focused on general self-harm (n = 3) [89][90][91] and the risks associated with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) (n = 2). 92 Population size of young people participating in included studies…”

Section: 30-93mentioning

confidence: 99%

An evidence synthesis of risk identification, assessment and management for young people using tier 4 inpatient child and adolescent mental health services

Hannigan

Edwards

Evans

et al. 2015

Health Services and Delivery Research

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BackgroundInpatient child and adolescent mental health services are one part of a complex system, and exist to meet the needs of young people with the greatest mental health difficulties.ObjectivesThe research question was ‘What is known about the identification, assessment and management of risk (where “risk” is broadly conceived) in young people (aged 11–18 years) with complex mental health needs entering, using and exiting inpatient child and adolescent mental health services in the UK?’Data sourcesThe two-phase Evidence for Policy and Practice Information and Co-ordinating Centre approach was used. In phase 1, scoping searches were made using two databases with an end date of March 2013. Phase 2 centred on the search for citations relating to the risks to young people of ‘dislocation’ and ‘contagion’. Searches were made using 17 databases, with time limits from 1995 to September 2013. Websites were searched, a call for evidence circulated and references of included citations reviewed.Review methodsPriority risk areas for phase 2 were decided in collaboration with stakeholders including through consultations with young people and the mother of a child who had been in hospital. All types of evidence relating to outcomes, views and experiences, costs and cost-effectiveness, policies, and service and practice responses in the areas of ‘dislocation’ and ‘contagion’ for young people (11–18 years) using inpatient mental health services were considered. A staged approach to screening was used. Data were extracted into tables following guidance from the Centre for Reviews and Dissemination or tables developed for the review. Quality was assessed using appraisal checklists from the Effective Public Health Practice Project or the Critical Skills Appraisal Programme or devised by previous reviewers. No papers were excluded on the grounds of quality, and all materials identified were narratively synthesised.ResultsIn phase 1, 4539 citations were found and 124 included. Most were concerned with clinical risks. In phase 2, 15,662 citations were found and 40 addressing the less obvious risks of ‘dislocation’ and ‘contagion’ were included, supplemented by 20 policy and guidance documents. These were synthesised using these categories: Dislocation: Normal Life; Dislocation: Identity; Dislocation: Friends; Dislocation: Stigma; Dislocation: Education; Dislocation: Families; and Contagion. No studies included an economic analysis or economic evaluation. The importance to stakeholders of these less obvious risks contrasted with the limited quantity and quality of research capable of informing policy, services and practice in these areas.LimitationsIncluded studies were of variable quality. Data derived could not be used to inform an economic modelling of NHS costs or to analyse cost-effectiveness. Other limitations were the search for only English-language materials and the use of umbrella concepts (‘dislocation’ and ‘contagion’).ConclusionsThe less obvious risks are important, but little evidence exists to support their identification, assessment and management. This has implications for services, and a programme of research is recommended to generate new knowledge.FundingThe National Institute for Health Research Health Services and Delivery Research programme.

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Anxiety and impulsivity levels identify relevant subtypes in adolescents with at-risk behavior

Cited by 63 publications

References 31 publications

Systematic review of pharmacotherapy of disruptive behavior disorders in children and adolescents

Systematic review of pharmacotherapy of disruptive behavior disorders in children and adolescents

Inhibitory control and emotional stress regulation: Neuroimaging evidence for frontal–limbic dysfunction in psycho-stimulant addiction

An evidence synthesis of risk identification, assessment and management for young people using tier 4 inpatient child and adolescent mental health services

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