Anxiety and depression symptoms among ovarian cancer patients in China: a cross-sectional study^†

Abstract

ObjectiveTo investigate the prevalence of cancer-related depression and anxiety in western China among patients with ovarian cancer and analyze their influencing factors.MethodsIn this prospective cross-sectional study, qualified patients were asked to fill in questionnaires. Multivariate analysis and binary logistic regression analysis were used to test the associations among symptoms of depression and anxiety, coping styles, and influencing factors.ResultsA total of 270 ovarian cancer inpatients who met the criteria for participation in the study completed the questionnaires. The levels of depression and anxiety that prevailed in ovarian cancer patients were 47.03% and 57.77%, respectively. Among them, 90.38% of cancer-related anxiety patients and 91.33% of cancer-related depression patients showed mild symptoms. The chi-square test showed that there were statistically significant differences (P < 0.05) in the fields of education level and income. T-test showed that cancer-related depression and anxiety were associated with coping style, and the difference had statistical significance (P < 0.05). Furthermore, multivariate analysis showed that the education level and coping style were the independent influencing factors of depression and anxiety.ConclusionsThe present study suggested that about half of the ovarian cancer patients had with depression and anxiety symptoms. The majority of the cancer-related depression and symptoms were mild. Educational level and coping style should be considered during the interventions of cancer-related depression and anxiety.

The Prevalence of Depression and Anxiety in Women with Ovarian Cancer: An Updated Systematic Review and Meta-Analysis of Cross-Sectional Studies

“…As a result of searching electronic databases, 1371 articles were obtained, of which 1221 remained after removing duplicates. In the next step, after screening based on the title, abstract, and full text based on the inclusion and exclusion criteria, 18 studies [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] were selected for meta-analysis (Fig. 1), of which 17 studies [13][14][15][16][17][18][20][21][22][23][24][25][26][27][28][29][30] reported the prevalence of depression and 16 studies [13][14][15][16][17][18][19][22][23][24][25][26][27][28]…”

“…1), of which 17 studies [13][14][15][16][17][18][20][21][22][23][24][25][26][27][28][29][30] reported the prevalence of depression and 16 studies [13][14][15][16][17][18][19][22][23][24][25][26][27][28][29][30] reported the prevalence of anxiety in women with ovarian cancer. Of 18 included studies, 6 were conducted in Australia [13,15,20,25,26,30], 2 in the USA [16,17], 2 in the United Kingdom [18,19], 2 in China [22,23], and one in each of the following countries: Norway [14], Czech Republic [21], Thailand [24], the Netherlands [27], Italia [28], and Poland…”

“…After combining these results, the pooled prevalence of depression in American women with ovarian cancer was 36% (95% CI: 10% -64%). Two studies [22,23] with a sample size of 468 people were conducted in China. After combining these studies, the pooled prevalence of depression in Chinese women with ovarian cancer was 47 (95% CI: 42% -53%).…”

“…Subgroup analysis based on age showed that six studies [14,15,23,24,28,29] with a sample size of 1280 people determined the prevalence of depression in women with ovarian cancer, aged equal to or less than 55 years. After combining these results, the pooled prevalence of depression was estimated as 30% (95% CI: 12% -50%) in women with ovarian cancer, aged equal to or less than 55 years.…”

“…In this section, 16 studies [13][14][15][16][17][18][19][22][23][24][25][26][27][28][29][30] determined the prevalence of anxiety in women with ovarian cancer, with the lowest prevalence in the survey of Camara C et al [27] with a value of 5% (95% CI: 1% -8%) and the highest prevalence in the study of Stafford L et al [25] with a value of 77% (95% CI: 68% -87%). In these studies, a total of 2442 women with ovarian cancer were studied, of whom 737 people suffered from an anxiety disorder.…”